Results 71 to 80 of about 8,548 (258)

Recursive Time Series Prediction Modeling of Long-Term Trends in Surface Settlement During Railway Tunnel Construction

open access: yesCivilEng
The surface settlement of railroad tunnels is dynamically updated as the construction progresses, exhibiting complex nonlinear characteristics. The accuracy of the on-site nonlinear regression fitting prediction method needs to be improved.
Feilian Zhang   +5 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Integrated Wavelet-Grey-Neural Network Model for Heritage Structure Settlement Prediction

open access: yesBuildings
To address the issue of insufficient prediction accuracy in traditional GM(1,1) models caused by significant nonlinear fluctuations in time-series data for ancient building structural health monitoring, this study proposes a wavelet decomposition-based ...
Yonghong He   +4 more
doaj   +1 more source

Settlement Manipulation in Prediction Markets

open access: yes
Prediction markets increasingly list contracts settling on an asset price that holders can move by trading the underlying. We build a model showing that such contracts transfer wealth from prediction-market liquidity traders to manipulators and harm price discovery in the underlying, even as it becomes more liquid. After the launch of Polymarket's five-
Dai, David, Jia, Ruizhe, Yu, Shihao
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Study on GA–ANN-Based Prediction of Paving Time of Cement-Stabilized Layer above Ultra-High-Filled Subgrade

open access: yesBuildings
In mountainous areas, high-filled subgrade often experiences significant post-construction settlement. Prematurely paving the cement-stabilized gravel layer on an unstable subgrade can easily lead to subsequent cracking.
Wenjie Liu   +7 more
doaj   +1 more source

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