Results 81 to 90 of about 801,999 (333)

The Impact of System Softness on Haines Jumps and Drainage in Porous Media

open access: yesWater Resources Research
Haines jumps are abrupt movements of fluid interfaces accompanied by sudden changes in capillary pressure during multiphase flow in porous media. They are a fundamental pore‐scale mechanism influencing displacement patterns and efficiency.
Bowen Zhang   +3 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Numerical investigation on the influence of groundwater flow on long-term heat extraction performance of deep borehole heat exchanger array

open access: yesGeothermal Energy
Groundwater convection is commonly observed in real-world projects, particularly in coastal and groundwater-abundant regions. To accurately evaluate the heat extraction capacity of the deep borehole heat exchanger (DBHE) considering groundwater flow, a ...
Xiong Yang   +6 more
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Prospects for Settlement of Minor Crimes Through Village Judiciary in Indonesia [PDF]

open access: gold, 2023
Muhammad Azil Maskur   +3 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

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