Results 81 to 90 of about 257,863 (298)
Gongye shui chuliA nickel soap wastewater-based photocatalytic Fenton oxidation-coagulation coupling process was developed to enhance the removal efficiency of organic pollutants and overcome the limitations of conventional Fenton processes.
QI Yuetong +7 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Provincial allocation of carbon emission quotas for China’s 2030 carbon peak target
Carbon Balance and ManagementDeveloping a fair and effective carbon emissions quotas (CEQ) allocation plan is crucial for China. This study uses the constructed threshold-STIRPAT extended model to predict the carbon peak in China’s 30 provinces.
Ning Wang +6 more
doaj +1 more source
BuildingsAs China transitions into a deeply aging society, the elderly population’s growth has driven a rapid increase in elderly care institutions and facilities during the “13th Five-Year Plan” period, rising by over 235% compared to the “12th Five-Year Plan ...
Tianye Liu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
, 2021 The baseline assessment study for the future impact evaluation of informal settlements targeted for upgrading set out to collect data for use by the Department of Human Settlements (DHS) to address the following: Strengthen implementation and improve
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Research progress of coagulation treatment technology in the wastewater from oilfield
Gongye shui chuliThe development of domestic oilfield is directly related to the national energy security. The domestic oilfield development and production resulted in the generation of large amount of wastewater.
JIN Xin +10 more
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source