Results 131 to 140 of about 1,046,218 (306)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Geometric function theory in several complex variables
, 1990 This is an expanded English-language version of a book by the same authors that originally appeared in the Japanese. The book serves two purposes. The first is to provide a self-contained and coherent account of recent developments in geometric function ...
Ochiai, Takushiro, Noguchi, Junjiro
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Demonstratio MathematicaThis study is devoted to exploring the existence and the precise form of finite-order transcendental entire solutions of second-order trinomial partial differential-difference equations L(f)2+2hL(f)f(z1+c1,z2+c2)+f(z1+c1,z2+c2)2=eg(z1,z2)L{(f)}^{2}+2hL(f)
Xu Hong Yan, Haldar Goutam
doaj +1 more source
, 2015 Analytic continuation is a central issue in Several Complex Vari-ables, starting with the Hartogs Phenomenon. We examine the applicationsof techniques of analytic continuation in Complex Geometry for irreduciblebounded symmetric domains Ω and their dual
Mok, N
core
The stars at infinity in several complex variables
, 2023 This text reviews certain notions in metric geometry that may have further applications to problems in complex geometry and holomorphic dynamics in several variables.
Karlsson, Anders
core
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
On the Zariski closure of a germ of totally geodesic complex submanifold on an arithmetic variety
, 2012 published_or_final_versio
Mok, N
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source