Pairwise causal discovery in biochemical networks: A survey on directionality inference within complex networks from stationary observations. [PDF]
Leibovich N, Cuperlovic-Culf M.
europepmc +1 more source
Uniqueness problem of meromorphic mappings in several complex variables for movingtargets
Nevanlinna showed that for two nonconstant meromorphic functions on the complex plane, if they have the same inverse images counting multiplicities for four distinct values, then they coincide up to a Mobius transformation, and if they have the same ...
Tu, Zhen-Han
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A Comprehensive Mendelian Randomization Study of Bidirectional Causal Relationships Between Pain and Mental Disorders [Letter]. [PDF]
Han J, Ye Y, Mao Y, Lou L.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Surgical approaches for the treatment of posterior malleolar fracture: which one to choose? [PDF]
Fernández-Rojas E +3 more
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Closing the Global Action Plan is not Reasonable for the Materiai in My Commentary that States Closing the Gap. [PDF]
Joshi C.
europepmc +1 more source
A note on functions of several complex variables [PDF]
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

