Results 121 to 130 of about 5,249,440 (315)

Comparative Study of Lexical Semantic Ability in Hearing and Hearing Impaired Adults

Function and Disability Journal, 2018
Background and Objective: People with more lexical semantic abilities can be more achieved in communicating with others, and in understanding the spoken or written words or sentences of others.
Fahimeh Mousavi, Mohammad Sadegh Jenabi, Mohammad Kamali, Hasan Sanei, Sanaz Azari, Younes Amiri-Shavaki   +5 more
doaj  

Severe dementia: A review on diagnoses, therapeutic management and ethical issues

Dementia & Neuropsychologia
North American data show that in the year 2000 around 4.5 million people had a diagnosis of dementia and more than a half were at moderate or severe stages of the disease.
Lilian Schafirovits-Morillo, Cláudia Kimie Suemoto   +1 more
doaj   +1 more source

Legislative Hall [PDF]

, 1987
A first-day cover featuring Legislative Hall in the state capitol of Dover. The great seal of the state of Delaware is below Legislative Hall and above text sharing that Delaware is the first state of the Union.
Severe, Martin
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Whole-body vs. selective head cooling and target temperature strategies for neonatal HIE: a meta-analysis of long-term outcomes

Frontiers in Pediatrics
ObjectiveTo systematically evaluate the differential long-term outcomes—including mortality, severe disability, and specific neurodevelopmental domains (language, learning, memory)—associated with various therapeutic hypothermia strategies for moderate ...
Yuping Lin, Lifeng Hu, Libin Xie, Zihui Wei   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Dover Stamp Club [PDF]

, 1987
A first-day cover featuring the ratification of the Constitution by the State of Delaware on December 7, 1787.
Severe, Martin
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Long-Acting Muscarinic Antagonists for the Treatment of Difficult-to-Treat and Severe Asthma: A Narrative Review Focusing on Inflammation from Bench to Bedside

Journal of Inflammation Research
Luigino Calzetta,1 Gian Marco Manzetti,2 Elena Pistocchini,2 Renato Federico Lauro,2 Shima Gholamalishahi,2 Mario Cazzola,2 Paola Rogliani2 1Unit of Respiratory Clinical Pharmacology, Department of Clinical Science and Translational Medicine, University ...
Calzetta L, Manzetti GM, Pistocchini E, Lauro RF, Gholamalishahi S, Cazzola M, Rogliani P   +6 more
doaj  

State capitol [PDF]

, 1987
A first-day cover featuring an image of Delaware's capitol in blue hues. Above the Capitol Building is the Delaware flag; the bottom left of the image credits Art Craft.
Severe, Martin
core