Results 201 to 210 of about 4,841,505 (283)

Airborne spread of severe acute respiratory syndrome coronavirus 2 between rooms in a sealed, mechanically ventilated ward: Evidence from a hospital outbreak investigation. [PDF]

PLoS One
Ishigaki Y, Fujita N, Kato T, Ochiai T, Kuroboshi H, Sakane A, Asai N.   +6 more
europepmc   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Effect of nucleic acid concentration method on Severe Acute Respiratory Syndrome Coronavirus 2 detection sensitivity in aircraft wastewater. [PDF]

J Med Microbiol
El-Malah SS, Alhaj Sulaiman A, Jabbar KA, Prator CA, Gratalo D, Goldfarb D, Mahmoud KA.   +6 more
europepmc   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Efficacy and safety of remdesivir for patients with severe acute respiratory syndrome coronavirus 2 infection: A systematic review of randomized controlled trials. [PDF]

Indian J Pharmacol
Meena J, Agarwal A, Sandhu A, Pradhan P, Singh M.   +4 more
europepmc   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Maternal, perinatal, neonatal, and postpartum outcomes following Severe Acute Respiratory Syndrome - Coronavirus-2 infection in pregnancy: a World Health Organization multi-country prospective cohort study. [PDF]

BMC Glob Public Health
WHO COVID-19 & Pregnancy Cohort Study Group.
europepmc   +1 more source

Lung Ultrasound for the Detection of Radiologic Progression of Interstitial Lung Abnormalities in Patients With Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Interstitial lung disease (ILD) is an important extra‐articular manifestation of rheumatoid arthritis (RA) associated with high mortality and morbidity. Lung ultrasonography (LUS) has recently emerged as a possible screening tool. We assessed the role of LUS in monitoring radiologic progression and the development of new interstitial lung ...
Marie Vermant, Valerie Van Ballaer, Joseph Jacob, Tine Follet, Ryoko Egashira, Kenny Anseele, Heleen Cypers, Laurens J. De Sadeleer, Nico De Crem, Tinne Goos, Barbara Neerinckx, Veerle Taelman, Nathalie Veyt, Alexandros Kalkanis, Patrick Verschueren, Wim A. Wuyts   +15 more
wiley   +1 more source

2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase Inhibition. [PDF]

ChemMedChem
Cernicchi G, Nizi MG, Emmolo R, Persoons L, Laporte M, Jochmans D, Romeo I, Pepe G, Milite C, Campiglia P, Spezzini J, Martelli A, Brogi S, Esposito F, Felicetti T, Massari S, Manfroni G, Sabatini S, Sbardella G, Alcaro S, Neyts J, Corona A, Tramontano E, De Jonghe S, Tabarrini O.   +24 more
europepmc   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source