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Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies

open access: yesInternational Journal of Antimicrobial Agents, 2020
The emergence and rapid spread of novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as a potentially fatal disease is swiftly evolving public health crises worldwide.
Atul K. Sharma   +3 more
semanticscholar   +1 more source

Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern. The fragile balance between infections and autoimmunity [PDF]

open access: yes, 2020
On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
Diamanti, A. P.   +4 more
core   +2 more sources

Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States

open access: yesEmerging Infectious Diseases, 2020
The etiologic agent of an outbreak of pneumonia in Wuhan, China, was identified as severe acute respiratory syndrome coronavirus 2 in January 2020.
J. Harcourt   +33 more
semanticscholar   +1 more source

Severe reinfection with severe acute respiratory syndrome coronavirus 2 in a nursing home resident: a case report

open access: yesJournal of Medical Case Reports, 2021
Background The topic of natural immunity related to severe acute respiratory syndrome coronavirus 2 remains controversial. Although evidence suggests postinfection immunity can be achieved, there have been reported cases of reinfection with similar or ...
Nimrah Bader   +2 more
doaj   +1 more source

Detectable Serum Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load (RNAemia) Is Closely Correlated With Drastically Elevated Interleukin 6 Level in Critically Ill Patients With Coronavirus Disease 2019

open access: yesClinical Infectious Diseases, 2020
Although the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load in respiratory specimens has been widely used to diagnose coronavirus disease 2019 (COVID-19), it is undeniable that serum SARS-CoV-2 nucleic acid ...
Xiaohua Chen   +11 more
semanticscholar   +1 more source

Coronavirus Disease 2019–Associated Thrombosis and Coagulopathy: Review of the Pathophysiological Characteristics and Implications for Antithrombotic Management

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by severe acute respiratory syndrome coronavirus‐2, which has posed a significant threat to global health.
Luis Ortega‐Paz   +3 more
doaj   +1 more source

Human Kidney is a Target for Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection

open access: yesmedRxiv, 2020
BACKGROUND The outbreak of a novel coronavirus (SARS-CoV-2, previously provisionally named 2019 novel coronavirus or 2019-nCoV) since December 2019 in Wuhan, China, has become an emergency of major international concern. Apart from the respiratory system,
B. Diao   +14 more
semanticscholar   +1 more source

Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study. [PDF]

open access: yes, 2020
BackgroundAn outbreak of COVID-19 in Iran has spread throughout the country. Identifying the epidemiological characteristics of this disease will help to make appropriate decisions and thus control the epidemic. The aim of this study was characterization
Abbaszadeh, Sepideh   +19 more
core   +1 more source

Evidence Supporting Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 While Presymptomatic or Asymptomatic

open access: yesEmerging Infectious Diseases, 2020
Recent epidemiologic, virologic, and modeling reports support the possibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from persons who are presymptomatic (SARS-CoV-2 detected before symptom onset) or asymptomatic ...
Nathan W. Furukawa, J. Brooks, J. Sobel
semanticscholar   +1 more source

Symptomatic severe acute respiratory syndrome coronavirus 2 reinfection in a lupus patient treated with hydroxychloroquine: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Hydroxychloroquine and chloroquine have been used for hospitalized coronavirus disease 2019 patients because of their antiviral and anti-inflammatory function.
Astrid Muyldermans   +9 more
doaj   +1 more source

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