Results 171 to 180 of about 483,790 (291)

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, EarlyView.
The SARS‐CoV‐2 nucleocapsid (N) protein facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone. The Omicron BA.5 variant shows reduced chaperone activity compared to the Wuhan wild‐type protein. Although phosphorylation has no effect on wild‐type N, phosphomimetic modification of BA.5 N restores its RNA ...
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Association between wildfire smoke exposure and pediatric emergency department visits for headache

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The purpose of this study was to determine whether short‐term exposure to wildfire smoke is associated with emergency department visits for headache in children and adolescents. Background Wildfires are becoming increasingly common and are associated with numerous adverse health outcomes.
Hannah F. J. Shapiro, Amy A. Gelfand, Daniel J. Shapiro, Holly Elser, Chen Chen, Joan A. Casey   +5 more
wiley   +1 more source

Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal‐Associated Invariant T (MAIT) Cell Function

Immunology, EarlyView.
Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng, Eimear K. Ryan, Michael Bennett, Christy Clutter, Jackson G. Cacioppo, Jeffrey Aubé, Andy E. Hogan, Daniel T. Leung   +7 more
wiley   +1 more source

Permissiveness of American bison to infection with severe acute respiratory syndrome coronavirus-2. [PDF]

Sci Rep
Palmer MV, Buckley A, Cassmann ED, Olsen SC, Nielsen DW, Putz EJ, Seger H, Chandler JC, Boggiatto PM.   +8 more
europepmc   +1 more source

Detection of SARS coronavirus in plasma by real-time RT-PCR [PDF]

, 2003
Chan, PKS, Garson, JA, Grant, PR, Sung, JJY, Tam, JS, Tedder, RS   +5 more
core   +1 more source

The novel coronavirus (2019-nCoV) in pregnancy: What we need to know [PDF]

, 2020
Carbone, Floriana Ilma, Saccone, Gabriele, Zullo, Fulvio   +2 more
core   +1 more source

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID

Immunology, EarlyView.
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat, Priyanka Khatri, Youssif M. Ali, Chanuka H. Arachchilage, Gregory Demopulos, Kirsten Baillie, Kelly L. Miners, Kristin Ladell, Samantha A. Jones, Helen E. Davies, David A. Price, Wioleta M. Zelek, B. Paul Morgan, Wilhelm J. Schwaeble, Nicholas J. Lynch   +14 more
wiley   +1 more source

Noninvasive Monitoring of Inflammatory Processes by Myeloid Cell-Directed PET Tracers in an Experimental Severe Acute Respiratory Syndrome Coronavirus 2 Infection Model. [PDF]

J Nucl Med
Stammes MA, Koopman G, Wagner TR, Traenkle B, Kaiser PD, Mooij P, van der Werff N, Acar RF, Böszörményi KP, Blaess S, Pezzana S, Reischl G, Maurer A, Langermans JAM, Rothbauer U, Kneilling M, Sonanini D.   +16 more
europepmc   +1 more source

Bridging the implementation gap in MCABC inventory management: from a taxonomy to practical archetypes

International Transactions in Operational Research, EarlyView.
Abstract Despite increasing demands for resilient and sustainable supply chains, inventory management often relies on outdated single‐criterion analyses. While multi‐criteria ABC (MCABC) analyses provide a theoretically mature assessment of resilience‐sustainability‐benefit trade‐offs in inventory, their adoption remains limited due to fragmented ...
Lukas Grützner, Michael H. Breitner
wiley   +1 more source

Application of oral fluid for quantitative nucleic acid and antibody detection of the severe acute respiratory syndrome coronavirus 2. [PDF]

Front Public Health
Song R, Li J, Wang Y, Huang Q, Geng Y, Ding X, Duan X, Wen C, Tang Y, Kang L, Huang F, Dong M, Dong J, Chen X.   +13 more
europepmc   +1 more source