Results 181 to 190 of about 19,340 (214)

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, Volume 45, Issue 4, Page 599-623, July/August 2026.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Coronavirus M Protein Hijacks Toll‐Interacting Protein (TOLLIP) to Suppress NF‐κB Signaling and Promote Immune Evasion

MedComm, Volume 7, Issue 7, July 2026.
Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang, Lu Kang, Yu Zhong, Songjun Shao, Senren Xue, Changliang Liu, Xiaoqi Zheng, Jing‐Wen Lin, Yu Chen, Fengming Luo, Huajing Wan   +10 more
wiley   +1 more source

CD8+ Tissue‐Resident Memory T Cells in Health and Disease

MedComm, Volume 7, Issue 7, July 2026.
CD8+ TRM cells are at the center of immunity, mediating potent local innate and adaptive immune responses. While TRM cells mediate protective immunity against infections and tumors, they also contribute to pathological inflammation in autoimmune conditions.
Yu‐Han Ai, Ting‐Ting Xu, Sen Lin, Meng‐Yu Xiao, Yun‐Xia Lin, Hao‐Wen Ma, Yue‐Yang Liu, Yao‐Jie Wang, Lu‐Ning Yin, Mei Huang, Yong‐Da Liu, Chao Zhu, Xiao‐Ting Zhu, Ji‐Hang Yuan   +13 more
wiley   +1 more source

Exploring the Impact of the Relationship Among Nurses' Resilience, Work Environment Satisfaction, and Intention to Stay After the Local COVID‐19 Outbreak Situation Changed in Taiwan: A Pre‐ and Post‐Survey Study

Nursing Open, Volume 13, Issue 7, July 2026.
ABSTRACT Aim To investigate the impact on nurses' resilience, work environment satisfaction and intention to stay during the COVID‐19 pandemic, we explored the relationships among these three characteristics. Study Design A pre‐ and post‐survey study design.
Ru‐Wen Liao, Chu‐Hsuan Cheng, I‐Shiang Tzeng   +2 more
wiley   +1 more source

Voice Outcomes of Patients Intubated for Critical COVID Illness: A Multicenter Study

OTO Open, Volume 10, Issue 3, July-September 2026.
Abstract Objective Characterize the long‐term vocal outcomes of patients who required ICU care for COVID‐19 infection. Study Design Prospective cohort study. Setting Multi‐institutional North American Airway Collaborative Study. Methods Patients with a COVID‐19 diagnosis requiring ICU admission were identified via ICD‐10 codes and recruited after ...
Francesco F. Caruana, Alexander Gelbard, David Francis, Michael J. Pitman, Elena P. Kennedy, Joel Blumin, Jonathan Bock, Matthew Clary, Quinlyn Axelson, Laura Matrka, Patrick McGarey, James Daniero, Phillip Weissbrod, Yin Yiu, Daniel Gorelik, Robert J. Morrison, Shady Soliman   +16 more
wiley   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Novel Recruitment, Data Collection, and Safety Reporting Methods in the Era of COVID‐19: Design of a Post‐Emergency Use Authorization COVID‐19 Vaccination Safety‐Surveillance Study

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 7, July 2026.
ABSTRACT Purpose Within one week of the Food and Drug Administration granting the COVID‐19 vaccine Emergency Use Authorization, the HERO‐Together study launched. We describe how the study utilized novel methods for streamlined enrollment and longitudinal data collection to efficiently monitor early and long‐term safety of the COVID‐19 vaccine.
Cherise Wong, Katherine Kendrick, Laura Webb, Lauren Cohen, M. Patricia McAdams, Heather Rubino, Patrick Caubel, Emily O'Brien   +7 more
wiley   +1 more source

The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors

Protein Science, Volume 35, Issue 7, July 2026.
Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley   +1 more source

From Norovirus to Andes Hantavirus: Indirect Viral Transmission and Emerging Prevention Strategies for Cruise Ship and Confined Environments

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT Cruise ships and other confined travel settings remain highly vulnerable to infectious disease outbreaks. During 2025–2026, multiple norovirus outbreaks and the rare Andes hantavirus outbreak associated with the MV Hondius cruise highlighted the continuing public health challenges posed by both highly transmissible enteric viruses and emerging
Umme Laila Urmi, Mark D. P. Willcox
wiley   +1 more source

Ocular Manifestations of Canine Parvovirus in Juvenile Dogs: Tear Production, Intraocular Pressure, Fundoscopic Findings, and Ultrasonographic Measurements

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Naturally acquired canine parvovirus infection in juvenile dogs was associated with reduced tear production, ocular hypotony, corneal epithelial defects, and fundoscopic abnormalities, suggesting ocular surface and posterior segment involvement and supporting ophthalmic screening during clinical evaluation.
Yalcin Alper Ozturan, Rahime Yaygingul, Mehmet Gultekin, Murat Sarierler, Ibrahim Akin   +4 more
wiley   +1 more source