Results 171 to 180 of about 19,340 (214)

Efficacy of Low‐Dose Naltrexone in Women With Fibromyalgia Syndrome: A 12‐Month Randomised, Double‐Blind, Placebo‐Controlled Single‐Centre Clinical Trial (INNOVA Study)

European Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background Low‐dose naltrexone (LDN) has been used off‐label for fibromyalgia syndrome (FMS) for over a decade, supported by small crossover trials. The INNOVA study evaluated the safety and efficacy of LDN 4.5 mg versus placebo on pain intensity over 12 months in women with FMS.
Carla Rodríguez‐Freire, Jaime Navarrete, Antoni Rozadilla‐Sacanell, Juan P. Sanabria‐Mazo, Beatriz del Pino‐Gaya, Xavier Borràs, Albert Feliu‐Soler, Juan V. Luciano   +7 more
wiley   +1 more source

High‐frequency oscillations after acute hemorrhagic traumatic brain injury: insights into posttraumatic epilepsy development

Epilepsia, Volume 67, Issue 7, Page 3612-3628, July 2026.
Abstract Objective The development of posttraumatic epilepsy after traumatic brain injury (TBI) is potentially identifiable by measuring biomarkers of epileptogenesis, namely pathological high‐frequency oscillations (pHFOs). pHFOs are promising candidates, but it remains uncertain whether they can be detected early after TBI in clinical settings.
Kseniia Kriukova, Lin Li, Richard J. Staba, Misque Boswell, Tuba Asifriyaz, Rachel Thomas, James J. Gugger, Mohamad Shamas, Ramon Diaz‐Arrastia, Manuel Buitrago Blanco, Jerome Engel, Paul M. Vespa, Dominique Duncan, on behalf of the EpiBios4Rx investigators, Denes Agoston, Alicia K. Au, Michael Bell, Ben Churn, Jan Claassen, Ramon Diaz‐Arrastia, Jerome Engel, Brandon Foreman, Aristea Galanopoulou, Emily Gilmore, Martin Hunn, Nathalie Jette, Andrew Morokoff, Solomon L. Moshé, Terence O'Brien, Joshua Laing, Piero Perucca, Kristine H. O'Phelan, Asla Pitkanen, Eric Rosenthal, Frederick Willyerd, Lara Zimmermann, Ben Ellingson, Buitrago Blanco, Daniel Correa, Dana Harrar, Thomas P. Bleck, Brian Appavu, Aaron Struck, Baxter Allen, Inna Keselman, Jeff Kennedy, Victor Ferastraoaru, Ji Yeoun Yoo, Arthur W. Toga   +48 more
wiley   +1 more source

Predictors of Mortality in COVID‐19 Patients Presenting With Gastrointestinal Bleeding: A Retrospective Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Coronavirus disease 2019 (COVID‐19), since its outbreak, has been a potentially fatal disorder. Gastrointestinal bleeding (GIB) with a notable prevalence of 1.5%–3% has been identified as a prominent cause of death in COVID‐19 patients.
Mobin Rasapour, Hamid Mohajer, Erfan Sabouri   +2 more
wiley   +1 more source

Impact of COVID‐19 on Subsequent Lung Function in Childhood: A Systematized Review

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims The SARS‐CoV‐2 infection can lead to transiently altered lung function in adults, but data is less clear in children. We aimed to summarize the available evidence about respiratory outcomes after COVID‐19 in childhood. Methods We conducted a literature search on post‐COVID‐19 lung function tests (LFT) on the Medline and ...
Benedetta De Santis, Francesca Baldo, Giovanni Vento, Stefano Nobile   +3 more
wiley   +1 more source

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

Tracking COVID‐19 Severity and Progression Through Amines and Lipid Mediators

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Coronavirus disease 2019 (COVID‐19) exhibits a broad spectrum of severity, ranging from mild to critical cases. To reduce mortality and costs, tailored early interventions for at‐risk patients are essential. This study elucidates the association between longitudinal metabolomic profiles and COVID‐19 severity and progression.
Melissa Goris, Merys Valdez, Lieke Lamont, Wei Yang, Amy Harms, Naama Karu, Sabine Bos, Jelte Geerlings, Tom Ottenhoff, Roula Tsonaka, Anna HE Roukens, M. Sesmu Arbous, Simone A. Joosten, Thomas Hankemeier, Alida Kindt, In collaboration with BEAT‐COVID group, M.S. Arbous, B.M. van den Berg, S. Cannegieter, C.M. Cobbaert, A. van der Does, J.J.M. van Dongen, J. Eikenboom, M.C.M. Feltkamp, A. Geluk, J.J. Goeman, M. Giera, T. Hankemeier, M.H.M. Heemskerk, P.S. Hiemstra, C.H. Hokke, J.J. Janse, S.P. Jochems, S.A. Joosten, M. Kikkert, L. Lamont, J. Manniën, T.H.M. Ottenhoff, M.R. del Prado, N. Queralt Rosinach, M. Roestenberg, M. Roos, A.H.E. Roukens, H.H. Smits, E.J. Snijder, F.J.T. Staal, L.A. Trouw, R. Tsonaka, A. Verhoeven, L.G. Visser, J.J.C. de Vries, D.J. van Westerloo, J. Wigbers, H.J. van der Wijk, R.C. van Wissen, M. Wuhrer, M. Yazdanbakhsh, M. Zlei   +57 more
wiley   +1 more source

Virus‐Specific Impact of Respiratory Viruses on Adult Emergency Department Outcomes

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Few studies have examined the impact of community‐acquired respiratory viruses (CRVs) on emergency department visits and outcomes in adults. This study aimed to characterize the epidemiology of CRV infections and assess associations between virus types and clinical outcomes.
Daijiro Nabeya, Takeshi Kinjo, Naoya Nishiyama, Wakaki Kami, Wakako Arakaki, Takuma Okamoto, Kenta Kuniyoshi, Mao Nishiyama, Hideta Nakamura, Shusaku Haranaga, Jiro Fujita, Kazuko Yamamoto, Soichi Shiiki, Tomoo Kishaba   +13 more
wiley   +1 more source

Assessment of Residual‐Serum SARS‐CoV‐2‐N‐Antigen Testing for Hospital Surveillance in Germany

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Routine SARS‐CoV‐2 surveillance in hospitals is crucial for preventing in‐hospital transmission, especially among elderly and multimorbid patients. While RT‐PCR testing is sensitive, it is resource‐intensive, and rapid antigen tests lack sensitivity.
Jasmin Weninger, Aleko Zedginidze, Antonios Katsounas, Michael Pohl, Abdurrahman Coskun, Roman Wölfel, Mustafa Özcürümez   +6 more
wiley   +1 more source

A post hoc analysis of linaclotide in pediatric patients with functional constipation and neurodevelopmental disorders

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 1, Page 21-28, July 2026.
Abstract Objectives Functional constipation (FC) is common in children with comorbid neurodevelopmental disorders (NDD) and its optimal treatment may be challenged by adherence and medication tolerability issues in this population. We assessed the efficacy and safety of linaclotide in pediatric patients with FC and NDD.
Hannibal Person, Jeffrey S. Hyams, Rinarani M. Sanghavi, Valentina Shakhnovich, Katherine Kosch, Moming Li, Danielle D'Achino, Julie Khlevner, Bruno P. Chumpitazi, Miguel Saps   +9 more
wiley   +1 more source

Design of Nanocarriers for Kidney Targeted Delivery of Nucleic Acid Therapeutics

Macromolecular Bioscience, Volume 26, Issue 7, July 2026.
Nucleic acid therapeutics have been investigated to expand their applications to renal genetic disorders. This review summarizes key considerations in the design and fabrication of nanocarriers for the systemic delivery of nucleic acid therapeutics to the kidneys.
Jun Hyuk Lee, Junku Han, Sehwan Park, Hyejung Mok   +3 more
wiley   +1 more source