Results 181 to 190 of about 569,433 (400)

Modernising epidemic science: enabling patient-centred research during epidemics [PDF]

, 2016
Background: Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security threat. As an outbreak begins, epidemiological investigations and traditional public health responses are generally mounted ...
Horby, Peter W., Rojek, Amanda M.
core   +3 more sources

Human Leukocyte Antigen Susceptibility Map for Severe Acute Respiratory Syndrome Coronavirus 2

Journal of Virology, 2020
Individual genetic variation may help to explain different immune responses to a virus across a population. In particular, understanding how variation in HLA may affect the course of COVID-19 could help identify individuals at higher risk from the ...
Austin Nguyen, Julianne K. David, Sean K. Maden, Mary A. Wood, Benjamin R. Weeder, Abhinav Nellore, Reid F. Thompson   +6 more
semanticscholar   +1 more source

Humoral Immune Response to Breakthrough Infection With SARS‐CoV‐2 Delta and Omicron Variants

iLABMED, EarlyView.
Patients with breakthrough infections of the Omicron variant exhibited significantly higher levels of neutralizing antibodies and IgG than those infected with the Delta variant. By contrast, Delta‐infected patients showed higher levels of IgM and IgA than Omicron‐infected patients.
Xihong Zhang, Chungen Qian, Huixia Gao, Li Yang, Yuling Wang, Ying Huang, Xin Zhang, Aidong Feng, Calvin Q. Pan, Yuzhu Shi, Ying Chen, Bangning Cheng, Erhei Dai   +12 more
wiley   +1 more source

Coronavirus in Continuous Flux: From SARS‐CoV to SARS‐CoV‐2

Advanced Science, 2020
The world is currently experiencing a global pandemic caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which causes severe respiratory disease similar to SARS.
Yetian Dong, Tong Dai, Jun Liu, Long Zhang, Fangfang Zhou   +4 more
doaj   +1 more source

A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) [PDF]

, 2019
Background The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was first described in 2012 and attracted a great international attention due to multiple healthcare associated outbreaks.
Al-Ali, Anfal Y., Al-Tawfiq, Jaffar A., Momattin, Hisham   +2 more
core   +1 more source

Unveiling Origin Pitfalls in Metagenomic Surveillance for Emerging Infectious Diseases: Parvoviruses as a Model

iMetaMed, EarlyView.
A diverse reagent‐associated virome, including parvoviruses, misleads zoonotic surveillance. By leveraging large language models (ChatGPT‐4o), we construct a virus discovery data framework (PVDDC) and ParvoDB to access and correct host misattributions, thereby enhancing the accuracy of metagenomic surveillance for emerging zoonotic diseases.
Peng Zhao, Jie Dong, Hong Liu, Data Research and Curation Team, Ying Xue, Ting Zhang, Hongtao Sui, Yongfeng Hu, Jiang Du, Haoxiang Su, Qi Jin, Fan Yang   +11 more
wiley   +1 more source

Severe Acute Respiratory Syndrome–Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research [PDF]

, 2021
OBJECTIVES: Since the beginning of the coronavirus disease 2019 pan-demic, hundreds of thousands of patients have been treated in ICUs across the globe. The severe acute respiratory syndrome–associated coronavirus 2 virus enters cells via the angiotensin-
Armaignac, Donna Lee
core   +1 more source

RTTAP: Empowering metatranscriptomic data analysis with a read‐based total‐infectome taxonomic solution

iMetaOmics, EarlyView.
Metatranscriptomic data analysis is a complex task due to its sheer volume and the need for sophisticated bioinformatics tools. To address this, we developed the Read‐based Total‐infectome Taxonomic Analysis Pipeline (RTTAP), an automated pipeline for metatranscriptomic data analysis that eliminates the need for users to manually select databases ...
Wei Jiang, Herui Liao, Mang Shi, Liangjun Chen, Yanni Sun   +4 more
wiley   +1 more source

Molecular aspects of MERS-CoV [PDF]

, 2017
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Ahmed, Shamsah H., Al-Tawfiq, Jaffar A., Bazzi, Ali M., Rabaan, Ali A.   +3 more
core   +1 more source

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) [PDF]

Trends in Genetics, 2020
Saak V. Ovsepian, Saak V. Ovsepian, Valerie B. O’Leary   +2 more
openaire   +3 more sources