Results 231 to 240 of about 569,433 (400)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Severe acute respiratory syndrome coronavirus 2: Oncology-related perceptions

Indian Journal of Health Sciences and Biomedical Research KLEU, 2021
Atin Singhai, Parul Jain, Ranjan Solanki
doaj   +1 more source

Role of the DPP4 Receptor in SARS‐CoV Entry: Insights From Docking and Molecular Dynamics Simulations

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein–receptor interactions play a critical role in viral entry and pathogenesis. While ACE2 is the primary receptor for SARS‐CoV, the role of DPP4 as potential coreceptor remains underexplored. This study investigates the binding mechanisms and dissociation dynamics of the SARS‐CoV/DPP4, SARS‐CoV/ACE2 and MERS‐CoV/DPP4 complexes using ...
Patrícia Pereira Duzi Carvalho, Nelson Augusto Alves   +1 more
wiley   +1 more source

The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection

, 2020
Rasoul Mirzaei, Farzad Mahdavi, Fariba Badrzadeh, Seyed Reza Hosseini‐Fard, Maryam Heidary, Ali Salimi Jeda, Tayeb Mohammadi, Mahdane Roshani, Rasoul Yousefimashouf, Hossein Keyvani, Mohammad Darvishmotevalli, Melika Zarei Sani, Sajad Karampoor   +12 more
openalex   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Covid-19 Ontology Engineering-Knowledge Modeling of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) [PDF]

, 2020
Vinu Sherimon, Sherimon P.C, Renchi Mathew, M. Sandeep, Varanasi Rahul, Khalid Shaikh, Hilal Khalid, Huda Salim   +7 more
openalex   +1 more source

Severe acute respiratory syndrome coronavirus 2 and forensic pathology [PDF]

Medicine, Science and the Law, 2021
openaire   +3 more sources

Microneedle delivery systems for vaccines and immunotherapy

Smart Molecules, EarlyView.
This paper reviews the preparation methods and materials of microneedles for drug delivery, summarizes the structures and types of microneedle systems, analyzes the influence of antigens and adjuvants on the efficacy of microneedle vaccines, and reviews the current application status of microneedles in the fields of vaccines and immunotherapy by ...
Haiyao Jia, Jinyuan Liu, Mengqian Shi, Manzar Abbas, Ruirui Xing, Xuehai Yan   +5 more
wiley   +1 more source

Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection

Einstein (São Paulo)
In December 2019, a series of patients with severe pneumonia were identified in Wuhan, Hubei province, China, who progressed to severe acute respiratory syndrome and acute respiratory distress syndrome.
Thiago Domingos Corrêa, Gustavo Faissol Janot de Matos, Bruno de Arruda Bravim, Ricardo Luiz Cordioli, Alejandra del Pilar Gallardo Garrido, Murillo Santucci Cesar de Assuncao, Carmen Silvia Valente Barbas, Karina Tavares Timenetsky, Roseny dos Reis Rodrigues, Hélio Penna Guimarães, Roberto Rabello Filho, Frederico Polito Lomar, Farah Christina de La Cruz Scarin, Carla Luciana Batista, Adriano José Pereira, João Carlos de Campos Guerra, Bárbara Vieira Carneiro, Ricardo Kenji Nawa, Rodrigo Martins Brandão, Antônio Eduardo Pereira Pesaro, Moacyr Silva Júnior, Fabricio Rodrigues Torres de Carvalho, Cilene Saghabi de Medeiros Silva, Ana Claudia Ferraz de Almeida, Marcelo Franken, Marcele Liliane Pesavento, Raquel Afonso Caserta Eid, Leonardo José Rolim Ferraz   +27 more
doaj   +1 more source

The use of hepatitis C virus NS3/4A and secreted alkaline phosphatase to quantitate cell–cell membrane fusion mediated by severe acute respiratory syndrome coronavirus S protein and the receptor angiotensin-converting enzyme 2

, 2007
Chih-Fong Chou, Shuo Shen, Geetha Mahadevappa, Seng Gee Lim, Wanjin Hong, Yee‐Joo Tan   +5 more
openalex   +1 more source