Results 231 to 240 of about 627,596 (387)

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

1726. Characterization of humoral immune responses to COVID-19 vaccination in children in Canada: interim analysis from the Severe acute respiratory syndrome-related coronavirus 2 PRevalence In children and youNG adults in British Columbia (SPRING) Study [PDF]

, 2023
Gabrielle N. Gaultier, Mandy Lo, Brynn McMillan, Amy Huei‐Yi Lee, Bing Cai, Tony Harn, Sofia Bartlett, Muhammad Morshed, Inna Sekirov, Kate Zinszer, Elinor Simons, Piush J. Mandhane, Jonathon L. Maguire, Agatha N. Jassem, Manish Sadarangani   +14 more
openalex   +1 more source

Mesoporous Materials for Electrochemical Biosensors: From Broad Structure to Silica Film

Small, EarlyView.
This review showcases how mesoporous materials advance biosensing, spanning from material classes and fabrication strategies to the unique role of silica films as functional sensing platforms. With tunable porosity, high surface area, and versatile chemistry, these materials enhance selectivity and signal amplification in biosensors.
Vinh Khanh Ho, Tuan‐Khoa Nguyen, Sina Jamali, Nam‐Trung Nguyen   +3 more
wiley   +1 more source

Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection

Einstein (São Paulo)
In December 2019, a series of patients with severe pneumonia were identified in Wuhan, Hubei province, China, who progressed to severe acute respiratory syndrome and acute respiratory distress syndrome.
Thiago Domingos Corrêa, Gustavo Faissol Janot de Matos, Bruno de Arruda Bravim, Ricardo Luiz Cordioli, Alejandra del Pilar Gallardo Garrido, Murillo Santucci Cesar de Assuncao, Carmen Silvia Valente Barbas, Karina Tavares Timenetsky, Roseny dos Reis Rodrigues, Hélio Penna Guimarães, Roberto Rabello Filho, Frederico Polito Lomar, Farah Christina de La Cruz Scarin, Carla Luciana Batista, Adriano José Pereira, João Carlos de Campos Guerra, Bárbara Vieira Carneiro, Ricardo Kenji Nawa, Rodrigo Martins Brandão, Antônio Eduardo Pereira Pesaro, Moacyr Silva Júnior, Fabricio Rodrigues Torres de Carvalho, Cilene Saghabi de Medeiros Silva, Ana Claudia Ferraz de Almeida, Marcelo Franken, Marcele Liliane Pesavento, Raquel Afonso Caserta Eid, Leonardo José Rolim Ferraz   +27 more
doaj   +1 more source

Alterations of the oral microbiome in patients reinfected with SARS‐CoV‐2 omicron variants

VIEW, EarlyView.
We studied the oral microbiome (the community of microbes in the mouth) in people who were reinfected with the omicron variant of SARS‐CoV‐2 and compared it with healthy individuals and other respiratory illness groups. By sequencing tongue‐coating samples from large cohorts, we identified microbial shifts linked to Omicron reinfection and built a ...
Benchen Rao, Yongjian Zhou, Tong Ren, Hongxia Liang, Lei Li, Yakun Xu, Haiyu Wang, Xiaoping Wang, Xiaoli Ni, Xiaoning Wang, Hanmeng Liu, Xiaoli Jin, Qiaoxia Chen, Xuemei Wang, Yawen Zou, Ying Sun, Zhigang Ren, Zujiang Yu   +17 more
wiley   +1 more source

Recent advances of non‐invasive sensors for smart wearable respiratory monitoring

VIEW, EarlyView.
Respiration contains rich physiological and pathological information, making it one of the most fundamental and continuous vital signs. Respiration monitoring is a non‐invasive and simple, but incredibly powerful, tool for assessing health, managing disease, and tracking fitness.
Jianhui Chen, Baoxiang Yang, Chang Peng, Bao Yang, Licheng Zhou, Zhenyu Jiang, Zejia Liu, Yiping Liu, Liqun Tang   +8 more
wiley   +1 more source

Impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection and disease-2019 (COVID-19) on the quality of life of rheumatoid arthritis patients in Benin

, 2020
Zavier Zomalhèto, Calixte Assogba, Hilaire Dossou-yovo   +2 more
openalex   +1 more source

Accelerated T-Cell Immunosenescence in Cytomegalovirus-Seropositive Individuals After Severe Acute Respiratory Syndrome Coronavirus 2 Infection [PDF]

, 2023
Pablo Álvarez-Heredia, Irene Reina-Alfonso, Jose Joaquín Domínguez-del-Castillo, Carmen Gutiérrez-González, Fakhri Hassouneh, Alexander Batista-Duharte, Ana-Belén Pérez, Raquel Tarazona, Rafael Solana, Alejandra Pera   +9 more
openalex   +1 more source

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response

Diabetes & Metabolic syndrome: clinical Research & Reviews, 2020
I. Astuti, Ysrafil
semanticscholar   +1 more source

Crystallographic fragment screening against SARS‐CoV‐2 nonstructural protein 1 using the F2X‐Entry Screen and a newly developed fragment library

Acta Crystallographica Section D, EarlyView.
Two crystallographic fragment screening campaigns against SARS‐CoV‐2 nonstructural protein 1 resulted in the identification of 21 new hits.Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) continues to threaten global health. This underpins the need for novel therapeutics against this virus.
Frank Lennartz, Jan Wollenhaupt, Melanie Oelker, Paula Fröling, Uwe Mueller, Anke Deckers, Christoph Grathwol, Stefan Bräse, Nicole Jung, Manfred S. Weiss   +9 more
wiley   +1 more source