CD38‐Targeting Peptide Vaccine Ameliorates Aging‐Associated Phenotypes in Mice
Shangcheng Yu et al. revealed that CD38‐targeting peptide vaccine ameliorated aging‐associated physical and cognitive phenotypes in mice. CD38‐vaccine selectively depletes CD38+ myeloid cells, improves glucose tolerance, and enhances oxygen consumption.
Shangcheng Yu+10 more
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Recovery from Myalgic Encephalomyelitis/Chronic Fatigue syndrome developed after severe acute respiratory syndrome coronavirus 2 vaccination: A case report. [PDF]
Kurotori I, Sasao W, Abe M.
europepmc +1 more source
Aged CD11b+ cells exhibit impaired IRF7 activation and reduced SNARE protein expression, leading to delayed interferon responses and diminished cytokine secretion. These dual deficits may contribute to the heightened susceptibility of older individuals to severe outcomes following SARS‐CoV infection.
Yu‐Xuan Wu+10 more
wiley +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
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In-depth analysis of the risk factors for persistent severe acute respiratory syndrome coronavirus 2 infection and construction of predictive models: an exploratory research study. [PDF]
Zhang J+10 more
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ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga+7 more
wiley +1 more source
Severe acute respiratory syndrome coronavirus 2 infection unevenly impacts metabolism in the coronal periphery of the lungs. [PDF]
Laro J+5 more
europepmc +1 more source
Update on andrological effects of SARS‐CoV‐2 infection and COVID‐19: An overview review
Abstract Background Evidence indicates a wide range of andrological alterations in patients with the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS‐CoV‐2) infection and Coronavirus Disease 2019 (COVID‐19). Aim To provide an update on the andrological effects of SARS‐CoV‐2 infection and COVID‐19.
Giuseppe Lisco+7 more
wiley +1 more source
A Case Report of a Boy With Clinically Mild Encephalopathy and a Reversible Splenial Lesion Associated With Severe Acute Respiratory Syndrome-Coronavirus 2 Infection. [PDF]
Moriuchi Y, Fuchigami T, Morioka I.
europepmc +1 more source