Results 261 to 270 of about 28,111,627 (303)

Multimerization of a rationally designed nanobody for enhanced avidity toward Aβ42 oligomers

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Alzheimer's disease affects tens of millions of people worldwide and is associated with the self‐assembly of the Aβ42 peptide into amyloid aggregates. Among the species formed during this process, soluble oligomeric intermediates are the most closely linked to neurotoxicity and are therefore an attractive target for both therapeutic and ...
Magdalena Nowinska   +3 more
wiley   +1 more source

Severe acute respiratory syndrome coronavirus-2 antibody prevalence in adults with HIV. [PDF]

open access: yesAIDS
Lucey M   +9 more
europepmc   +1 more source

Model‐Based Tacrolimus Dosing Using the Population Pharmacokinetic Analysis Under the Nirmatrelvir/Ritonavir Therapy

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACT Nirmatrelvir/ritonavir is an antiviral agent used against severe acute respiratory syndrome coronavirus 2 infection and inhibits cytochrome P450 3A and P‐glycoprotein. The concomitant use of nirmatrelvir/ritonavir markedly increases tacrolimus blood concentrations. Although temporary discontinuation or dose reduction of tacrolimus at the start
Kotaro Itohara   +14 more
wiley   +1 more source

Mucosal and Systemic Antibody Responses After Boosting With a Bivalent Messenger RNA Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine. [PDF]

open access: yesJ Infect Dis
Atmar RL   +36 more
europepmc   +1 more source

Therapeutic Strategy of Extracorporeal Carbon Dioxide Removal in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Combined With Central Airway Stricture: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 9, September 2026.
This case demonstrates that medium‐flow ECCO2R can serve as an effective bridge to therapy in AECOPD combined with central airway stricture, safely correcting refractory hypercapnia and providing a stable window for successful bronchoscopic stenting and ventilator weaning. ABSTRACT This case report highlights a novel and successful therapeutic strategy
Jingjing Deng   +3 more
wiley   +1 more source

Human guanylate-binding protein (GBP) 1 inhibits replication of severe acute respiratory syndrome coronavirus 2. [PDF]

open access: yesJ Virol
Farrukee R   +9 more
europepmc   +1 more source

Feeding and Husbandry Practices in Pet Ferrets (Mustela putorius furo): A Cross‐Sectional International Study

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Clearer recommendations and improved caregiver education are urgently needed to support optimal ferret welfare. ABSTRACT Background The domestic ferret (Mustela putorius furo) is an increasingly popular non‐traditional companion animal; however, limited information is available on how caregivers manage feeding and husbandry practices.
Erdem Danyer   +6 more
wiley   +1 more source

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