Dataset and analysis of genetic variability of Severe Acute Respiratory Syndrome Coronavirus 2 from different areas of the respiratory tract. [PDF]
Rojas-Pérez VE, Villegas EP.
europepmc +1 more source
Based on the retrospective analysis of a multicenter inpatient administrative database from Germany comprising 29 144 patient cases with atrial fibrillation who underwent left atrial catheter ablation, this study describes an ongoing trend toward increased utilization of interventional therapy that was not sustainably influenced by the COVID‐19 ...
Sebastian König +16 more
wiley +1 more source
Severe acute respiratory syndrome coronavirus 2-mediated dysregulation of drug processing genes is dependent on pathogenic variants, target site of infection, age, and sex. [PDF]
Nwabufo CK.
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Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco +17 more
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Correlation between severe acute respiratory syndrome coronavirus 2 infection and serum anti-neutrophil cytoplasmic antibody formation. [PDF]
Huang H +6 more
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We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson +12 more
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Trends in Group A <i>Streptococcus</i> Pharyngitis and Co-Infection with Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Observational Study. [PDF]
Takahashi H +14 more
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Nur77 Is Associated With Polyfunctional Properties in Virus‐Specific Human CD8+ T Cells
Nur77 is associated with a TCF‐1+ memory‐like, polyfunctional profile in virus‐specific human CD8+ T cells across acute‐resolved, vaccinated, and chronic viral infections, and its pharmacologic modulation in vitro enhances the functionality of dysfunctional HIV‐ and HBV‐specific CD8+ T cells in chronic co‐infections. ABSTRACT Human CD8+ T cells undergo
Fabiola Martel +14 more
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Effect of sample vortex mixing on severe acute respiratory syndrome coronavirus 2 nucleic acid testing: Comparative analysis of individual samples and sample pools. [PDF]
Jin G +6 more
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ABSTRACT Background and Aim Janus kinases/signal transducers and activators of transcription (JAK/STAT) pathway is crucial for various stages of immunity, from innate to adaptive responses. Type 1 IFNs activate JAK/STAT pathway by binding to receptors on JAK, phosphorylating STAT and upregulating interferon‐stimulated genes (ISGs) leading to cytokines ...
Esimebia Adjovi Amegashie +7 more
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