Results 101 to 110 of about 5,464,336 (251)

Rituximab for severe immune checkpoint inhibitor-related adverse events: a multicenter case series

Cancer Immunology, Immunotherapy
Background Immune checkpoint inhibitors (ICIs) can induce severe immune-related adverse events (irAEs) that are life-threatening and may be refractory to standard immunosuppressive therapy.
Stéphanie Hermabessiere, Benjamin Jauzelon, Steven Marmain, Axelle Wauthier, Philine Witkowski Durand Viel, Elodie Castille, Guillaume Padern, Anouck Lamoureux, Quentin Dominique Thomas, Xavier Quantin, Alexandre T. J. Maria, Cyrille Coustal   +11 more
doaj   +1 more source

Comparison of adverse events following the second/third dose of BNT162b2 in a medical institute in Japan

Heliyon
Background: Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are crucial for ending the pandemic of coronavirus disease 2019 (COVID-19).
Takahiro Namiki, Kazuhide Takada, Satoshi Hayakawa, Shihoko Komine-Aizawa   +3 more
doaj   +1 more source

Adverse events as a measure of patient safety in cancer care [PDF]

, 2020
“First, do no harm” is a fundamental element of health care and considered indistinguishable from the delivery of quality in health care. While cancer care has become more effective, it has also become more complex consequently increasing the risk for ...
Haukland, Ellinor Christin
core  

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Case report: Apalutamide-induced severe lethal cutaneous adverse effects in China

Frontiers in Immunology
IntroductionApalutamide is a novel agent for castration-resistant prostate cancer while skin rashes are the most common untoward reactions. Up to now, most of the reported dermatologic adverse events (dAEs) allocated to mild and moderate with a fair ...
Qi Wang, Qi Wang, Huali Cao, Xuetong Zhang, Huifeng Wu, Zhuangli Tang   +5 more
doaj   +1 more source

Major Adverse Cardiovascular Events and Mortality in Systemic Lupus Erythematosus Patients After Successful Delivery: A Population-based Study

, 2017
Background:Limited data exist regarding the incidence rate and hazard ratios (HRs) of major adverse cardiovascular events and mortality in the successful-delivery women with or without systemic lupus erythematosus.Methods:A retrospective, population ...
Wu, Lung-Sheng;Tang, Chao-Hsiun;Lin, Yu-Sheng;Lin, Chia-Pin;Hung, Sheng-Tzu;Hwa, Hsiao-Lin;Luo, Shue-Fen;Chu, Pao-Hsien, 華筱玲   +1 more
core   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Temporal Divergence of True and False Alarms in Pediatric Nocturnal Seizure Monitoring

Annals of Clinical and Translational Neurology, EarlyView.
The early‐morning surge in false seizure alarms supports exploring time‐ or state‐dependent detection thresholds to reduce false detections. ABSTRACT Seizure detection devices can improve the safety of children with epilepsy, yet high false alarms limit their clinical applicability.
Mohammad Shahbakhti, Anemoon T. Bosch, Job van der Palen, Franciscus S. Leijten, Johannes P. van Dijk, Richard H. C. Lazeron, Roland D. Thijs   +6 more
wiley   +1 more source

Safety of Allogeneic Umbilical Cord Blood Stem Cells Therapy in Patients with Severe Cerebral Palsy: A Retrospective Study

Stem Cells International, 2015
This retrospective study aimed to assess the safety of patients with severe cerebral palsy (CP), who received allogeneic umbilical cord blood stem cells (UCBSCs) treatment from August 2009 to December 2012 in Guangdong Provincial Hospital of Chinese ...
Mei Feng, Aili Lu, Hongxia Gao, Caiwen Qian, Jun Zhang, Tongxiang Lin, Yuanqi Zhao   +6 more
doaj   +1 more source