Background: Acute respiratory failure is a common reason for admission to the intensive care unit, and patients are frequently treated with high-flow nasal cannula oxygen therapy (HFNC).
Mai-Anh Nay +7 more
doaj +1 more source
Using an e-Delphi consensus technique to develop the Stressful Adverse Veterinary Events Support (SAVES) Framework [PDF]
Co-ordinated approaches to supporting veterinary practitioners in relation to adverse events are needed to mitigate associated practitioner stress and to prevent future occurrence.
Brennan, Marnie L +2 more
core +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
The Safety of Interferon‐Based Therapies in Chronic Hepatitis B Patients With Compensatory Cirrhosis
Aims The tolerance of patients with compensated hepatitis B cirrhosis to interferon (IFN) therapy remains controversial. Therefore, this study aimed to evaluate the safety of pegylated interferon‐alpha in chronic hepatitis B (CHB) patients with ...
Qiran Zhang +32 more
doaj +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
ADVERSE EVENTS DURING TREATMENT OF PATIENTS SUFFERING FROM MULTIPLE DRUG RESISTANT TUBERCULOSIS
Objective: to perform retrospective analysis of the ranges, structure, degree of severity and time of development of adverse events in tuberculosis patients with multiple drug resistance on treatment and to assess their impact on chemotherapy duration ...
D. Yu. Schegertsov +5 more
doaj +1 more source
One-Year Outcomes of Percutaneous Coronary Intervention in Patients with End-Stage Liver Disease
Background: Patients with cirrhosis and coronary artery disease (CAD) are at high risk for morbidity during surgical revascularization so they are often referred for complex percutaneous coronary intervention (PCI).
Daniel Y Lu +6 more
doaj +1 more source
Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998-2005. [PDF]
BACKGROUND: Adverse drug reactions (ADRs) are a frequent cause of mortality and morbidity to patients worldwide, with great associated costs to the healthcare providers including the NHS in England.
Majeed, Azeem +21 more
core +2 more sources

