Results 151 to 160 of about 1,676,317 (259)
Dengue virus infection: predictors for severe dengue.
Acta medica Indonesiana, 2011 Dengue virus (DENV) infection is a mosquito born disease that is endemic in all WHO regions, except European region, and may present a broad range of severity. It may appear as an asymptomatic condition, dengue fever (DF), or life threatening forms, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), or the currently defined severe ...
openaire +1 more source
Beyond the Battlefield: Examining Acute Kidney Injury in Yemen's Humanitarian Crisis
Public Health Challenges, Volume 5, Issue 3, September 2026.ABSTRACT Background Acute kidney injury (AKI) represents a growing yet under‐recognized public health threat in Yemen, where ongoing conflict has exacerbated vulnerabilities to infectious diseases and waterborne illnesses. Sepsis and severe volume depletion—secondary to diarrheal diseases such as cholera—are leading contributors to AKI incidence ...
Gamal Esam Ahmed Alsakkaf
wiley +1 more source
The Role of Cytokines in Activation of Coagulation and Fibrinolysis in Dengue Shock Syndrome [PDF]
, 2002 In a prospective clinical study of 50 patients with Dengue Shock Syndrome (DSS), we investigated the association of tumor necrosis factor- (TNF-), interleukin-1 (IL-1), IL-1 receptor antagonist (IL-1Ra), and IL-6 with activation markers of coagulation
Cate, Hugo ten +7 more
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Climate Justice and One Health Adaptation Policies in Public Health and Disaster Medicine
Public Health Challenges, Volume 5, Issue 3, September 2026.ABSTRACT Background Climate change is intensifying public health risks and placing increasing pressure on disaster medicine systems. These challenges require adaptation strategies that incorporate climate justice principles and the One Health framework.
Ioannis Adamopoulos +10 more
wiley +1 more source
Severe dengue progression beyond enhancement
Nature Immunology, 2023 Camila D. Odio +3 more
openaire +2 more sources
Reviews in Medical Virology, Volume 36, Issue 5, September 2026.ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria +5 more
wiley +1 more source
ChemistrySelect, Volume 11, Issue 33, 1 September 2026.This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira +8 more
wiley +1 more source
Design and Synthesis of a Potent, Cell Active Purine‐Based Amidoxime Against the Dengue Virus
ChemistrySelect, Volume 11, Issue 36, 22 September 2026.Scaffold hopping from our previous indolazepinone hit exemplifies purine SP‐835G with DENV2 EC50 0.1 µM, CC50>100 µM, clogP 3.61. Docking studies support its amidine metabolite operates as an allosteric inhibitor of DENV(pro). A flexible ether linker appears pivotal for enhancing binding and activity.
Dimitrios Kiousis +8 more
wiley +1 more source