Results 141 to 150 of about 57,777 (273)
Background: Severe dengue is a serious manifestation of dengue infection and one of the causes of death in children. Recognizing the prognostic factors for death in severe dengue, based on the 2009 WHO guidelines, can help provide appropriate management ...
Lidwina Elisabeth Setiana Salombe +3 more
doaj +1 more source
This review summarizes how extracellular vesicles from diverse pulmonary and extrapulmonary sources contribute to endothelial dysfunction in ARDS and evaluates emerging endothelial‐targeted therapies for their potential to mitigate EV‐mediated pathogenic mechanisms.
Mohammed Yaman Al Matni +3 more
wiley +1 more source
ABSTRACT Background Dengue (DG) is a growing global public health threat. Bangladesh continues to endure an increasing burden despite persistent vector‐control initiatives. Effective DG prevention relies on adequate community knowledge, favorable attitudes, and sustained protective practices.
Abu Reza Md. Towfiqul Islam +2 more
wiley +1 more source
Addressing Climate Driven Vector‐Borne Disease in West Africa
ABSTRACT Introduction Vector‐borne diseases (VBDs) pose a significant public health threat in West Africa, contributing to substantial morbidity and mortality, particularly among vulnerable populations. This region is highly susceptible to the effects of climate change due to its geographical location, dependence on rain‐fed agriculture, and fragile ...
Majani Edward +3 more
wiley +1 more source
Pathogenesis of severe dengue infection
G N, Malavige, G, Ogg
openaire +3 more sources
Dengue virus infection: predictors for severe dengue.
Dengue virus (DENV) infection is a mosquito born disease that is endemic in all WHO regions, except European region, and may present a broad range of severity. It may appear as an asymptomatic condition, dengue fever (DF), or life threatening forms, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), or the currently defined severe ...
openaire +1 more source
The Effect of Protein Tagging on Aggregation and Phase Separation
ABSTRACT Protein tags are widely used for purification, solubilization, detection, and imaging, yet they can substantially alter protein self‐assembly. This interference is particularly significant for intrinsically disordered proteins and low‐complexity domains, whose aggregation and phase separation are mediated by weak multivalent interactions that ...
Harunobu Saito, Kenji Sugase
wiley +1 more source
This study elucidates a novel antiviral mechanism of bacterial BEVs, which are shown to inactivate viruses by triggering membrane fusion, subsequent lysis and causing structural collapse. This direct virucidal action presents a promising broad‐spectrum strategy against diverse enveloped viruses.
Yaqi Gao +15 more
wiley +1 more source
CRISPR‐Cas13a/Cas12a Assisted Dual Portable and Visualized HDV and HBV Detection
ABSTRACT Co‐infection with both hepatitis B virus (HBV) and hepatitis D virus (HDV) can aggravate the severity of the end‐stage liver disease and accelerate its progression. However, no combined diagnostic method for HDV and HBV nucleic acids exists. In this study, we have developed a highly sensitive and specific dual detection method for HDV RNA and ...
Yuan Tian +10 more
wiley +1 more source
Reverse Genetics of Orthoflaviviruses: Strategies for Constructing Functional or Infectious cDNA
ABSTRACT Reverse genetics (RG) systems have transformed RNA virus research by enabling the recovery of recombinant viruses entirely from cloned cDNA. These platforms allow precise, hypothesis‐driven manipulation of viral genomes and support systematic phenotypic analyses in vitro and in vivo.
Young‐Min Lee
wiley +1 more source

