Results 141 to 150 of about 1,676,317 (259)

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Development and External Validation of Logistic Regression Models Integrating Conventional Complete Blood Count and Cell Population Data for Predicting RT‐PCR–Confirmed Dengue

Journal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
We developed logistic regression models integrating routine complete blood count (CBC) parameters and analyzer‐derived cell population data (CPD) to predict RT‐PCR–confirmed dengue infection and evaluated their performance across internal and external settings.
Lin‐Chen Hsu, Yu‐Ching Weng, Wen‐Chun Liu   +2 more
wiley   +1 more source

Prognostic factors for mortality in children with severe dengue: A single-centre retrospective cohort study

Heliyon
Background: Severe dengue is a serious manifestation of dengue infection and one of the causes of death in children. Recognizing the prognostic factors for death in severe dengue, based on the 2009 WHO guidelines, can help provide appropriate management ...
Lidwina Elisabeth Setiana Salombe, Nurnaningsih, Surya Adhi, Eggi Arguni   +3 more
doaj   +1 more source

Dengue Severity Score for Predicting Severe Dengue in Children: Need to Validate in Different Settings

Indian Pediatrics, 2023
Pathum, Sookaromdee, Viroj, Wiwanitkit
openaire   +2 more sources

APRI as a predictor of severe dengue fever

Journal of Family Medicine and Primary Care
ABSTRACT Introduction: The AST/platelet ratio index (APRI) is a well-researched indicator of liver fibrosis. Some studies have shown that APRI can be used as a predictor of severe dengue, but the data is limited.
Ajith K Jayachandran, Vincy Nelson, K Anisha   +2 more
openaire   +3 more sources

Clinical Manifestations Associated With RT‐PCR–Confirmed Zika Virus Infection Among Adults With Acute Rash in the Brazilian Amazon: A Cross‐Sectional Study

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Zika virus (ZIKV) infection remains a diagnostic challenge in regions where multiple arboviruses co‐circulate, particularly when laboratory testing is limited. Identifying distinguishing clinical features is therefore relevant for early case recognition. We conducted a cross‐sectional study including 1124 adults presenting with acute exanthema
Djane Clarys Baía‐da‐Silva, Yanka Karolinna Batista Rodrigues, Karolina Jeaneth Solórzano‐Chavarría, Luís Felipe Alho da Silva, Alexandre Vilhena Silva‐Neto, Luiz Henrique Gonçalves Maciel, Maria Paula Gomes Mourão, Marcia da Costa Castilho, Camila Botto‐Menezes   +8 more
wiley   +1 more source

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

MedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu, Yuqin Jin, Baochao Li, Jie Deng, Yiwen Zhou, Jinglun Zhang, Huang Li   +6 more
wiley   +1 more source

Estudo in vitro das citocinas envolvidas na resposta inflamatória de macrófagos murinos à infecção pelo vírus da dengue. [PDF]

, 2012
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.A dengue é uma doença que tem como agente etiológico o Dengue virus (DENV), da família Flaviviridae, do gênero Flavivirus.
Souza, Ingrid Larissa Melo de
core  

17‐epi‐Melianodiol, a new protolimonoid from Melia azedarach fruits, exhibits larvicidal activity and is associated with oxidative imbalance and midgut epithelial damage in Aedes aegypti larvae

Pest Management Science, Volume 82, Issue 9, Page 9240-9248, September 2026.
The bio‐guided phytochemical study resulted in the new compound 17‐epi‐melianodiol. The compound eliminated 100% of Aedes aegypti larvae at 100 ppm, causing pronounced morphological changes, cuticular damage, and extensive vacuolization. Abstract BACKGROUND In Brazil, Aedes aegypti is the primary vector of arboviruses such as dengue, chikungunya ...
Kethleen Duarte Crespo Soares, Thalya Soares Ribeiro Nogueira, Maria Aparecida Aride Bertonceli, Renata Rodrigues da Silva Robaina, Leticia Oliveira da Rocha, Francisco José Alves Lemos, Kátia Valevski Sales Fernandes, Raimundo Braz‐Filho, Ivo José Curcino Vieira   +8 more
wiley   +1 more source

Pathogenesis of severe dengue infection

Ceylon Medical Journal, 2012
G N, Malavige, G, Ogg
openaire   +3 more sources