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Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight. [PDF]

open access: yesNat Commun
Gregorova M   +22 more
europepmc   +1 more source
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CORRELATION OF DENGUE SCORE WITH THE SEVERITY OF DENGUE

GLOBAL JOURNAL FOR RESEARCH ANALYSIS, 2023
Background : Dengue is one of the most prevalent vector borne diseases worldwide. Dengue fever presents with wide clinical spectrum ranging from self limiting infection to severe dengue. Aim: Present study is done to correlate a novel indicator 'Dengue Score' with the severity of dengue.
Hemachandra P, Sharath N, Swathi Maiya
openaire   +1 more source

Biomarkers of severe dengue disease – a review [PDF]

open access: yesJournal of Biomedical Science, 2015
Dengue virus infection presents a wide spectrum of manifestations including asymptomatic condition, dengue fever (DF), or severe forms, such as dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) in affected individuals. The early prediction of severe dengue in patients without any warning signs who may later develop severe DHF is very ...
Oscar Perng
exaly   +3 more sources

Establishment of SMS Dengue Severity Score

Journal of the Association of Physicians of India, 2022
Background: Dengue infection is a disease that progresses rapidly to life-threatening conditions. Our goal was to develop a practical scoring system based on clinical profiles and routine tests to predict the severity of infection. Methods: This cross-sectional observational study included 500 patients with dengue infection.
Sudhir, Bhandari   +5 more
openaire   +2 more sources

Markers of Dengue Disease Severity

2009
Infection with one of the four serotypes of dengue virus (DENV) causes a wide spectrum of clinical disease ranging from asymptomatic infection, undifferentiated fever, dengue fever (DF) to dengue hemorrhagic fever (DHF). DHF occurs in a minority of patients and is characterized by bleeding and plasma leakage which may lead to shock. There are currently
Anon, Srikiatkhachorn, Sharone, Green
openaire   +2 more sources

Severe dengue: questioning the paradigm

Microbes and Infection, 2010
Severe dengue has been recognised for more than 200 years, but attempts to define, categorize and explain the condition have hotly contested for more than four decades. Resolution of this controversy may provide new insights for the management of patients.
openaire   +2 more sources

Risk factors and biomarkers of severe dengue

Current Opinion in Virology, 2020
Dengue virus infects several million people each year. Although usually a self-limiting disease, some patients can develop life-threatening severe complications, characterized by plasma leakage, hemorrhaging, and shock. The signs and symptoms of severe disease usually arise late in the disease course when patients are recovering and fever has subsided,
Abhay PS Rathore   +2 more
openaire   +2 more sources

Ferritin levels predict severe dengue

Infection, 2014
Currently, no tests are available to monitor and predict severity and outcome of dengue. To find potential markers that predict dengue severity, the present study validated the serum level of three acute-phase proteins α-1 antitrypsin, ceruloplasmin and ferritin in a pool of severe dengue cases compared to non-severe forms and other febrile illness ...
R, Soundravally   +4 more
openaire   +2 more sources

Current management of severe dengue infection

Expert Review of Anti-infective Therapy, 2016
Traditionally a disease mainly affecting the pediatric population, dengue burden has increased significantly in recent decades and adults with severe disease may become more common. There is currently no effective anti-viral agent available for the treatment of dengue and supportive care is the mainstay of management. Areas covered: We present a review
Tau Hong, Lee   +3 more
openaire   +2 more sources

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