Results 31 to 40 of about 3,133,095 (241)

Clinical relevance and discriminatory value of elevated liver aminotransferase levels for dengue severity. [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: Elevation of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) is prominent in acute dengue illness. The World Health Organization (WHO) 2009 dengue guidelines defined AST or ALT ≥ 1000 units/liter (U/L) as a criterion for ...
Linda K Lee, Victor C Gan, Vernon J Lee, Adriana S Tan, Yee Sin Leo, David C Lye   +5 more
doaj   +1 more source

Assessment of the Risk of Severe Dengue Using Intrahost Viral Population in Dengue Virus Serotype 2 Patients via Machine Learning

Frontiers in Cellular and Infection Microbiology, 2022
Dengue virus, a positive-sense single-stranded RNA virus, continuously threatens human health. Although several criteria for evaluation of severe dengue have been recently established, the ability to prognose the risk of severe outcomes for dengue ...
Su-Jhen Hung, Huey-Pin Tsai, Huey-Pin Tsai, Ya-Fang Wang, Wen-Chien Ko, Wen-Chien Ko, Jen-Ren Wang, Jen-Ren Wang, Jen-Ren Wang, Jen-Ren Wang, Sheng-Wen Huang   +10 more
doaj   +1 more source

Zika virus infection enhances future risk of severe dengue disease

Science, 2020
Double whammy Dengue and Zika virus epidemics have been lapping each other around the globe. These are closely related mosquito-borne viruses with about 40% homology within the envelope protein.
L. Katzelnick, César Narvaez, Sonia Arguello, Brenda Lopez Mercado, Damaris Collado, Oscarlett Ampie, Douglas Elizondo, Tatiana Miranda, Fausto Bustos Carillo, J. Mercado, Krista Latta, Amy J Schiller, Bruno Segovia-Chumbez, S. Ojeda, N. Sanchez, M. Plazaola, J. Coloma, M. Halloran, L. Premkumar, A. Gordon, Federico Narvaez, A. D. de Silva, G. Kuan, Á. Balmaseda, E. Harris   +24 more
semanticscholar   +1 more source

Comparing the Usefulness of the 1997 and 2009 WHO Dengue Case Classification: A Systematic Literature Review [PDF]

, 2014
The 1997 and 2009 WHO dengue case classifications were compared in a systematic review with 12 eligible studies (4 prospective). Ten expert opinion articles were used for discussion.
Farrar, J., Horstick, O., Jaenisch, T., Kroeger, Axel, Martinez, E., Ranzinger, S. R., See, L. L. C.   +6 more
core   +1 more source

Original antigenic sin in dengue - Hoskins effect

APIK Journal of Internal Medicine, 2023
Dengue is a mosquito-borne viral infection found in tropical and subtropical climates worldwide, mostly in urban and semiurban areas. The virus responsible for causing dengue is called dengue virus. There are four dengue virus serotypes, implying that it
Vasantha Kamath, Nisha Davy Olakkengi
doaj   +1 more source

Clinical evaluation of dengue and identification of risk factors for severe disease: protocol for a multicentre study in 8 countries [PDF]

, 2016
Background: The burden of dengue continues to increase globally, with an estimated 100 million clinically apparent infections occurring each year. Although most dengue infections are asymptomatic, patients can present with a wide spectrum of clinical ...
Ahmed, Firoz, Beck, Dorothea, Bethencourt, Sarah E., Brasil, Patricia, Caprara, Andrea, Chanpheaktra, Ngoun, Guzman, Maria, Jänisch, Thomas, Kieu, Nguyen Tan Thanh, Kumar, Varun, Lam, Phung Khanh, Magalhaes, Tereza, Mahendradhata, Yodi, Marques, Ernesto T. A., Marón Alfaro, Gabriela Maria, Merson, Laura, Nam, Nguyen Tran, Netto, Marco, Pleités Sandoval, Ernesto, Rosenberger, Kerstin, Safitri Laksono, Ida, Sarker, Malabika, Sathar, Jameela, See, Lucy Lum Chai, Simmons, Cameron, Souza Benevides, Bruno, Tam, Dong Thi Hoai, Tami, Adriana, Thanh Ha Quyen, Nguyen, Thi Phuong Dung, Nguyen, Van Kinh, Nguyen, Van Ngoc, Tran, Wills, Bridget, Wirths, Marius, Wolbers, Marcel, Yacoub, Sophie   +35 more
core   +2 more sources

Dysfunctional Innate Immune Responses and Severe Dengue

Frontiers in Cellular and Infection Microbiology, 2020
Although infection with the dengue virus (DENV) causes severe dengue, it causes a mild self-limiting illness in the majority of individuals. There is emerging evidence that an aberrant immune response in the initial stages of infection lead to severe ...
G. Malavige, C. Jeewandara, G. Ogg
semanticscholar   +1 more source

Antibody-dependent enhancement of severe dengue disease in humans

Science, 2017
Too much or too little—better than some Dengue fever is caused by a mosquito-transmitted flavivirus resembling Zika virus. Both viruses can cause severe diseases in humans with catastrophic sequelae.
L. Katzelnick, L. Gresh, M. E. Halloran, J. Mercado, G. Kuan, A. Gordon, Á. Balmaseda, E. Harris   +7 more
semanticscholar   +1 more source

Diagnostic performance of C-reactive protein level and its role as a potential biomarker of severe dengue in adults

Asian Pacific Journal of Tropical Medicine, 2020
Objective: To determine the relationship between C-reactive protein (CRP) level and the severity of dengue and the potential use of CRP in predicting acute dengue infection.
Raghavendra Rao, Snehal Nayak, Akhilesh K Pandey, Shobha U Kamath   +3 more
doaj   +1 more source

Age-associated differences in clinical manifestations and laboratory parameters during a dengue virus type 4 outbreak in Argentina [PDF]

, 2017
Infection by any of the four dengue virus (DENV) serotypes produces a wide spectrum of clinical illness in humans. Differences in clinical manifestation and severity have been associated with secondary heterologous infection, patient age, and virus ...
Bono, María M., Bruno, Agostina Alejandra, Byrne, Alana Brooke, Cordoba, María Teresa, Gutierrez, Francisco Guillermo, Polack, Fernando Pedro, Quipildor, Marcelo Omar, Talarico, Laura Beatriz   +7 more
core   +1 more source