Results 31 to 40 of about 3,091,060 (299)

VIRDOCD: a VIRtual DOCtor to Predict Dengue Fatality [PDF]

open access: yesExpert Systems. 2021;e12796, 2021
Clinicians make routine diagnosis by scrutinizing patients' medical signs and symptoms, a skill popularly referred to as "Clinical Eye". This skill evolves through trial-and-error and improves with time. The success of the therapeutic regime relies largely on the accuracy of interpretation of such sign-symptoms, analyzing which a clinician assesses the
arxiv   +1 more source

Assessment of the Risk of Severe Dengue Using Intrahost Viral Population in Dengue Virus Serotype 2 Patients via Machine Learning

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Dengue virus, a positive-sense single-stranded RNA virus, continuously threatens human health. Although several criteria for evaluation of severe dengue have been recently established, the ability to prognose the risk of severe outcomes for dengue ...
Su-Jhen Hung   +10 more
doaj   +1 more source

Zika virus infection enhances future risk of severe dengue disease

open access: yesScience, 2020
Double whammy Dengue and Zika virus epidemics have been lapping each other around the globe. These are closely related mosquito-borne viruses with about 40% homology within the envelope protein.
L. Katzelnick   +24 more
semanticscholar   +1 more source

Dysfunctional Innate Immune Responses and Severe Dengue

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Although infection with the dengue virus (DENV) causes severe dengue, it causes a mild self-limiting illness in the majority of individuals. There is emerging evidence that an aberrant immune response in the initial stages of infection lead to severe ...
G. Malavige, C. Jeewandara, G. Ogg
semanticscholar   +1 more source

Identification of potential antigenic peptides of Brucella through proteome and peptidome

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 523-534, January 2023., 2023
Based on proteomics and peptidomics, we identified 35 peptides from the Brucella proteome, which have the ability to bind MHC molecules and have the potential to be used in vaccine design. In addition, we also found four Brucella proteins containing the identified MHC‐I and MHC‐II binding peptides, which may be good candidate targets for designing ...
Meijuan Pei   +10 more
wiley   +1 more source

Non‐cytopathic bovine viral diarrhoea virus 2 induces autophagy to enhance its replication

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 405-416, January 2023., 2023
Ncp BVDV2 infection induced autophagy in MDBK cells via anti‐apoptosis and PKR suppression. Autophagy may play a role in establishing persistent infection caused by ncp BVDV. Abstract Background Bovine viral diarrhoea virus (BVDV) is an important viral pathogen that has an economic impact on the livestock industry worldwide.
Seung‐Uk Shin   +4 more
wiley   +1 more source

Diagnostic performance of C-reactive protein level and its role as a potential biomarker of severe dengue in adults

open access: yesAsian Pacific Journal of Tropical Medicine, 2020
Objective: To determine the relationship between C-reactive protein (CRP) level and the severity of dengue and the potential use of CRP in predicting acute dengue infection.
Raghavendra Rao   +3 more
doaj   +1 more source

Factors associated with severe dengue in Savannakhet Province, Lao People’s Democratic Republic [PDF]

open access: yes, 2021
This study aimed to describe the socio-demographic and clinical characteristics of dengue inpatients at a provincial hospital, and to identify factors associated with severe dengue.
Hamajima, Nobuyuki   +8 more
core  

A little less aggregation a little more replication: Viral manipulation of stress granules

open access: yesWIREs RNA, Volume 14, Issue 1, January/February 2023., 2023
Viruses depend entirely on host machinery and therefore aim to conquer the host and defeat its defenses to co‐opt its resources for its own replication. Improved understanding of how viruses counteract host immune responses such as stress granule assembly, detailed here, will inform future antiviral therapeutic strategies.
Matthew J. Brownsword, Nicolas Locker
wiley   +1 more source

A double whammy: The association between comorbidities and severe dengue among adult patients-A matched case-control study.

open access: yesPLoS ONE, 2022
BackgroundDengue infection is the most prevalent mosquito-borne viral infection globally. Concurrently, there has also been an upsurge of non-communicable comorbidities.
Wei Yao Ng   +12 more
doaj   +2 more sources

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