World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou +4 more
wiley +1 more source
Short-term pulmonary infiltrate with eosinophilia caused by asthma: a phenotype of severe, eosinophilic asthma? Five cases and a review of the literature [PDF]
, 2019 Min Sup Song +7 more
openalex +1 more source
The Impact of Environmental Pollution and Climate Change on Allergic Rhinitis and Lung Diseases
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Environmental pollution and climate change seriously affect human health, leading to the onset and exacerbation of chronic respiratory diseases, such as allergic rhinitis and lung diseases. Over the past several decades, increasing air pollution and environmental exposure owing to global urbanization, industrialization, and rapid economic ...
Xin‐Yan Liu +4 more
wiley +1 more source
Extension of mepolizumab injection intervals as potential of saving costs in well controlled patients with severe eosinophilic asthma [PDF]
, 2022 Georg Bölke +4 more
openalex +1 more source
Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu +7 more
wiley +1 more source
Comorbidities in patients with eosinophilic granulomatosis with polyangiitis and severe uncontrolled asthma: a retrospective analysis of US health insurance claims data [PDF]
Paul Dolin +9 more
openalex +1 more source
Effectiveness of Switching to Benralizumab in Severe Refractory Eosinophilic Asthma
, 2022 A. Gómez-Bastero Fernández +6 more
openalex +2 more sources
Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang +3 more
wiley +1 more source
Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice. [PDF]
, 2019 Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease.
Flayer, Cameron H +6 more
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