Results 191 to 200 of about 327,068 (394)

Benralizumab after sub‐optimal response to mepolizumab in severe eosinophilic asthma [PDF]

, 2020
Joanne Kavanagh, A Hearn, G d’Ancona, Jaideep Dhariwal, C Roxas, Linda Green, Louise Thomson, Mariana Fernandes, Brian D. Kent, Alexandra M. Nanzer, David J. Jackson   +10 more
openalex   +1 more source

Oral Immunotherapy in Peanut‐Allergic Adults Using Real‐World Materials

Allergy, EarlyView.
In 21 adults initiated on peanut oral immunotherapy (OIT), 67% tolerated at least 1000 mg on exit DBPCFC. Decreases in SPT size and increases in peanut‐ and Ara h 2‐specific IgG occurred in OIT participants but not in mechanistic controls (n = 9). Improvements were seen in FAQLQ‐AF and food neophobia scores.
Hannah Hunter, Kok Loong Ue, Victoria Cornelius, Ching Ching Yung, Iason Thomas, Olympia Tsilochristou, Janice Layhadi, Leonard Q. C. Siew, Carina Venter, Mohamed H. Shamji, Stephen J. Till   +10 more
wiley   +1 more source

Mepolizumab in the management of severe eosinophilic asthma in adults: current evidence and practical experience [PDF]

, 2016
Gilda Varricchi, Diego Bagnasco, Matteo Ferrando, Francesca Puggioni, Giovanni Passalacqua, Giorgio Walter Canonica   +5 more
openalex   +1 more source

Mepolizumab add-on therapy in a real world cohort of patients with severe eosinophilic asthma: response rate, effectiveness, and safety [PDF]

, 2020
Jermo J. van Toor, Sophie C. van der Mark, Jasper H. Kappen, J.C.C.M. in ’t Veen, Gert‐Jan Braunstahl   +4 more
openalex   +1 more source

Real-world study in severe eosinophilic asthma patients refractory to anti-IL5 biological agents treated with benralizumab in Spain (ORBE study) [PDF]

, 2021
Eva Martínez‐Moragón, Ismael García‐Moguel, Javier Nuevo, Gustavo Resler, I. Antépara, Ebymar Arismendi, Francisco Casas Maldonado, I. Dávila-González, Ismael García‐Moguel, José Luis Velasco-Garrido, Rocío Magdalena Díaz-Campos, Carmen Díaz-Donado, Beatriz G. Gálvez, José Luís Izquierdo Alonso, Antolín López-Viña, Eva Martínez‐Moragón, Cristina Navarro‐Soriano, Marta Palop-Cervera, Luis Pérez de Llano, Vicente Plaza, Miguel A. Racionero, Manuel J. Rial, Marina Carmen Rodríguez-Hernández, María Jesús Rodríguez‐Nieto, M.T. Martinez Zabaleta   +24 more
openalex   +1 more source

Recombinant Hypoallergenic Cat Allergy Vaccines

Allergy, EarlyView.
This study reports the construction and preclinical characterization of peptide‐carrier‐based vaccines combining all three important cat allergens (Fel d 1, Fel d 4 and Fel d 7) within single vaccine antigens, termed PreS‐Cat 1‐PreS‐Cat 5. Two subcutaneous immunizations of rabbits with PreS‐Cat 1‐5 induce equal or better antibodies blocking allergic ...
Daria Trifonova, Mirela Curin, Margarete Focke‐Tejkl, Zicheng Liu, Kristina Borochova, Pia Gattinger, Marianne van Hage, Hans Grönlund, Renata Kiss, Huey‐Jy Huang, Walter Keller, Ksenja Riabova, Antonina Karsonova, Michael Kundi, Inna Tulaeva, Daria Fomina, Alexander Karaulov, Rudolf Valenta   +17 more
wiley   +1 more source

Blood and sputum biomarkers in COPD and asthma: a review [PDF]

, 2016
Chronic obstructive pulmonary disease (COPD) and asthma are lung inflammatory diseases that represent major public health problems. The primary, and often unique, method to evaluate lung function is spirometry, which reflects disease severity rather than
Conti, V, De Marchis, L, Graziani, C, Ialleni, E, Leone, V, Munafò, G, Paone, G, Ramaccia, M, Salducci, M   +8 more
core  

Therapeutic switch from omalizumab to mepolizumab in patients with uncontrolled severe eosinophilic asthma: treatment effect by exacerbations in previous year and maintenance use of OCS [PDF]

, 2020
Mark Liu, Bradley E. Chipps, Xavier Muñoz, Gilles Devouassoux, Miguel Bergna, Steven G. Smith, Frank C. Albers, Robert G. Price, Jay Azmi, Dmitri Galkin, Kenneth R. Chapman   +10 more
openalex   +1 more source

Asthma Alleviation by Ginsenoside Rb1 via Promotion of Treg Proliferation and Inflammatory T Cell Inhibition

Allergy, EarlyView.
Screening of 250 natural products identified ginsenoside Rb1 (gRb1) as a potent modulator of regulatory T cells (Tregs) and inflammatory T cells. gRb1 increased IL‐10‐ and TGF‐β‐expressing Tregs while reducing Th17, Th1, and Th2 populations in both asthma model mice and human PBMCs.
Susanna Choi, Seung‐Ah Yoo, Kon‐Young Ji, Dong Ho Jung, Saseong Lee, Kang‐Gu Lee, Ki‐Myo Kim, Joo Young Lee, Myung‐A Jung, Bo‐Jeong Pyun, Jung Hur, Joon Young Choi, Chin Kook Rhee, Wan‐Uk Kim, Taesoo Kim   +14 more
wiley   +1 more source

Cross-organ Deployment of EOS Detection AI without Retraining: Feasibility and Limitation [PDF]

arXiv
Chronic rhinosinusitis (CRS) is characterized by persistent inflammation in the paranasal sinuses, leading to typical symptoms of nasal congestion, facial pressure, olfactory dysfunction, and discolored nasal drainage, which can significantly impact quality-of-life. Eosinophils (Eos), a crucial component in the mucosal immune response, have been linked
arxiv