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HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

Severe Eosinophilic Asthma and Severe Mixed Polyneuropathy: A Case of Eosinophilic Granulomatous Vasculitis With Polyangiitis and New Therapeutic Perspectives. [PDF]

open access: yesOpen Respir Arch
Lorenzo Martínez MDC   +6 more
europepmc   +1 more source
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Effects of benralizumab in a population of patients affected by severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps: a real-life study

Acta bio-medica : Atenei Parmensis, 2023
Background and aim: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a frequent comorbidity in severe eosinophilic asthma (SEA), which may contribute to the loss of asthma control. CRSwNP and SEA share a T2-mediated mechanism and the use of some anti-
C. Santomasi   +6 more
semanticscholar   +1 more source

Clusters of Severe Eosinophilic Asthma in a Korean Asthma Cohort

Respiration, 2021
<b><i>Background:</i></b> Targeted therapies have broadened the available treatment options for patients with severe eosinophilic asthma (SEA). However, differences in the magnitude of treatment responses among patients indicate the presence of various underlying pathophysiological processes and patient subgroups. <b><i&
Ji-Hyang Lee   +25 more
openaire   +2 more sources

Effect of Benralizumab on Mucus Plugs in Severe Eosinophilic Asthma

International Archives of Allergy and Immunology, 2023
Introduction: Mucus plugs are associated with airway obstruction in severe asthma and are involved in the formation of activated eosinophils. Benralizumab, an anti-interleukin-5 receptor antibody, markedly reduces not only peripheral blood eosinophils ...
Natsumi Sakai   +11 more
semanticscholar   +1 more source

The impact of steroid-sparing biologic therapies on weight loss in obese individuals with severe eosinophilic asthma

European Respiratory Journal, 2023
Extract Asthma and obesity are prevalent disorders with significant impact on public health. Obesity is a reported risk factor for the development of asthma and is associated with increased exacerbation rates, medication usage and higher symptoms scores ...
A. Nanzer   +13 more
semanticscholar   +1 more source

Mepolizumab in the Treatment of Severe Eosinophilic Asthma

Immunotherapy, 2015
IL-5 is crucial in the pathogenesis and evolution of eosinophilic asthma. Mepolizumab is a high-affinity humanized monoclonal antibody of the IgG1/k subtype that inhibits the binding of IL-5 to its receptor expressed on eosinophils, thereby inducing significant reduction in eosinophil circulation, as well as asthma exacerbations and corticosteroid ...
FAINARDI, Valentina   +2 more
openaire   +3 more sources

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