Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S.+8 more
core +2 more sources
Increased adaptive immune responses and proper feedback regulation protect against clinical dengue [PDF]
Dengue is the most prevalent arthropod-borne viral disease. Clinical symptoms of dengue virus (DENV) infection range from classical mild dengue fever to severe, life-threatening dengue shock syndrome. However, most DENV infections cause few or no symptoms.
arxiv +1 more source
Fatal patients with severe fever with thrombocytopenia syndrome in China
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease with a high case fatality rate. Key gaps remained as to the assessment of the clinical picture in fatal cases.A retrospective study was performed on 496 patients with fatal SFTS.
Jing Zhao+14 more
openaire +3 more sources
A case of SFTS coinfected with E. coli bacteremia
Background Severe fever thrombocytopenia syndrome virus (SFTSV) is the causative agent of severe fever thrombocytopenia syndrome (SFTS). SFTS is an emerging infectious disease, characterized by high fever, gastrointestinal symptoms, leukopenia ...
Hyungdon Lee+7 more
doaj +1 more source
Person-to-Person Transmission of Severe Fever With Thrombocytopenia Syndrome Bunyavirus Through Blood Contact [PDF]
Severe fever with thrombocytopenia syndrome bunyavirus is a newly discovered bunyavirus with high pathogenicity to human. The transmission model has been largely uncharacterized.
A. Xu+30 more
core +2 more sources
Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima+18 more
core
Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome [PDF]
Background/Aims Severe fever with thrombocytopenia syndrome (SFTS) is a viral hemorrhagic fever with a high fatality rate. However, effective treatments for SFTS cases not responded to supportive therapy have not been established.
Jeong Rae Yoo+5 more
doaj +1 more source
A case of left atrial myxoma accompanied by pancytopenia and pathological findings suggestive of pulmonary hypertension [PDF]
A case of left atrial myxoma accompanied by peculiar symptoms is reported. A 15-year old boy had progressive congestive heart failure and three episodes of acute attacks of panctyopenia. The anemia was accompanied by helmet-shaped, broken red blood cells,
Kawanishi, Koichi+3 more
core +1 more source
Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease caused by a novel bunyavirus, SFTS virus (SFTSV), with fatal outcome developed in approximately 17% of the cases. Thrombocytopenia is a hallmark feature of SFTS, and associated with a higher risk of fatal outcome, however, the pathophysiological involvement of platelet
Xiao-Kun Li+16 more
openaire +4 more sources
Recognition and Clinical Presentation of Invasive Fungal Disease in Neonates and Children [PDF]
AW and JK are supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of AberdeenPeer reviewedPublisher ...
King, Jill+4 more
core +1 more source