Results 51 to 60 of about 43,151 (205)

Loperamide Inhibits Replication of Severe Fever with Thrombocytopenia Syndrome Virus

Viruses, 2021
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by the SFTS virus (SFTSV). SFTS is mainly prevalent in East Asia.
Shuzo Urata, Jiro Yasuda, Masaharu Iwasaki   +2 more
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

The First Nationwide Surveillance of Severe Fever with Thrombocytopenia Syndrome in Ruminants and Wildlife in Taiwan

Viruses, 2023
Since the first discovery of severe fever with thrombocytopenia syndrome virus (SFTSV) in China in 2009, SFTSV has rapidly spread through other Asian countries, including Japan, Korea, Vietnam and Pakistan, in chronological order.
Chih-Ying Kuan, Tsai-Lu Lin, Shan-Chia Ou, Shih-Te Chuang, Jacky Peng-Wen Chan, Ken Maeda, Tetsuya Mizutani, Ming-Pin Wu, Fan Lee, Fang-Tse Chan, Chao-Chin Chang, Rui-Ling Liang, Sue-Fung Yang, Tsung-Ching Liu, Wu-Chun Tu, Hau-You Tzeng, Chia-Jung Lee, Chuen-Fu Lin, Hsu-Hsun Lee, Jhih-Hua Wu, Hsiao-Chien Lo, Kuan-Chieh Tseng, Wei-Li Hsu, Chi-Chung Chou   +23 more
doaj   +1 more source

Severe Fever and Thrombocytopenia Syndrome

Journal of Medicine and Life Science, 2013
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease, which is caused by thegenus Phlebovirus in the Bunyaviridae family. The syndrome was characterized by fever, gastrointestinal symptoms, neutropenia,and thrombocytopenia.
openaire   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

Clinical Pharmacology &Therapeutics, EarlyView.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow, Brendan Day, Esther H. Zhou, Corinne Woods, Nana Dwumfour, Jenni Y. Lee, Ilynn Bulatao, Sanae Cherkaoui, Manish Kalaria, Sonja Brajovic, Nabila Sadiq, Farideh Sistani, Maggie Lee, Grace Chai, Gerald Dal Pan   +14 more
wiley   +1 more source

SUDEP and mortality in developmental and epileptic encephalopathies: A meta‐analysis of randomized clinical trials and extension studies

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are associated with high premature mortality and increased risk of sudden unexpected death in epilepsy (SUDEP). However, epidemiological data remain limited, particularly for specific syndromes such as Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and infantile epileptic ...
Pierludovico Moro, Maria Sole Borioni, Adolfo Mazzeo, Enrico Cocchi, Carlo Di Bonaventura, Emanuele Cerulli Irelli   +5 more
wiley   +1 more source

Comprehensive Surveillance of Severe Fever with Thrombocytopenia Syndrome Virus in Patients with Acute Febrile Illness, Wild Rodents, and Trombiculid Larval Mites, Thailand

Emerging Infectious Diseases
Infection with severe fever with thrombocytopenia syndrome (Bandavirus dabieense) virus poses a substantial public health threat because of its high mortality rates and severe complications.
Piyada Linsuwanon, Yong Poovorawan, Keun Hwa Lee, Nutthanun Auysawasdi, Sirima Wongwairot, Chawin Limsuwan, Viboonsak Vuthitanachot, Surachai Leepitakrat, Sompong Vongpunsawasdi, Pornjarim Nilyanimit, Yossapong Paladsing, Erica Lindroth   +11 more
doaj   +1 more source

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

The value of cystatin C in evaluating the severity and prognosis of patients with severe fever with thrombocytopenia syndrome

BMC Infectious Diseases, 2022
Background Severe fever with thrombocytopenia syndrome (SFTS) is a novel emerging viral infectious disease. We explore the value of cystatin C (CysC) level in the evaluation of disease severity and prognosis in patients with SFTS.
Jiao Xie, Shenghua Jie
doaj   +1 more source

Hyperferritinemia as a Diagnostic Marker for Severe Fever with Thrombocytopenia Syndrome [PDF]

Disease Markers, 2017
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging viral disease in East Asia with high mortality. Few studies have examined markers that suggest SFTS in febrile patients. To determine useful biochemical markers for SFTS, patients aged 18 years or older with SFTS or microbiologically confirmed community-onset bacteremia with ...
Uh Jin Kim, Tae hoon Oh, Bansuk Kim, Seong Eun Kim, Seung-Ji Kang, Kyung-Hwa Park, Sook-In Jung, Hee-Chang Jang   +7 more
openaire   +2 more sources