Results 81 to 90 of about 54,939 (306)

Endothelial activation and dysfunction in severe fever with thrombocytopenia syndrome

PLOS Neglected Tropical Diseases, 2017
Pathogenesis of severe fever with thrombocytopenia syndrome (SFTS) has not been well described yet. Recent studies indicate that SFTSV could replicate in endothelial cells. Here we performed a case-control study to determine whether endothelial activation/dysfunction occurred in SFTSV infection and to identify the biomarkers reflecting endothelial ...
Xiao-Kun Li, Zhen-Dong Yang, Juan Du, Bo Xing, Ning Cui, Pan-He Zhang, Hao Li, Xiao-Ai Zhang, Qing-Bin Lu, Wei Liu   +9 more
openaire   +5 more sources

Current status of severe fever with thrombocytopenia syndrome in China [PDF]

Virologica Sinica, 2017
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by SFTS virus (SFTSV). SFTSV is associated with a high mortality rate and has been reported in China, South Korea and Japan. SFTSV undergoes rapid changes owing to evolution, gene mutations, and reassortment between different strains of SFTSV. In this review, we
Yi Song, Bing Hu, Deyin Guo, Jing Cheng, Faxian Zhan, Jing Li, Qin Wang, Jianbo Zhan, Jianbo Zhan   +8 more
openaire   +3 more sources

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Severe Fever with Thrombocytopenia Syndrome(SFTS) [PDF]

, 2015
特集journal ...
6374, 6375, シモダ, ヒロシ, マエダ, ケン, 下田, 宙, 前田, 健   +5 more
core   +1 more source

Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]

, 2015
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien, Cognasse, Fabrice, Garraud, Olivier, Gomez, Ricardo Martin, Hamzeh Cognasse, Hind, Pozzetto, Bruno, Schattner, Mirta Ana   +6 more
core   +2 more sources

Comprehensive Surveillance of Severe Fever with Thrombocytopenia Syndrome Virus in Patients with Acute Febrile Illness, Wild Rodents, and Trombiculid Larval Mites, Thailand

Emerging Infectious Diseases
Infection with severe fever with thrombocytopenia syndrome (Bandavirus dabieense) virus poses a substantial public health threat because of its high mortality rates and severe complications.
Piyada Linsuwanon, Yong Poovorawan, Keun Hwa Lee, Nutthanun Auysawasdi, Sirima Wongwairot, Chawin Limsuwan, Viboonsak Vuthitanachot, Surachai Leepitakrat, Sompong Vongpunsawasdi, Pornjarim Nilyanimit, Yossapong Paladsing, Erica Lindroth   +11 more
doaj   +1 more source

Identification of severe fever with thrombocytopenia syndrome virus genotypes in patients and ticks in Liaoning Province, China

Parasites & Vectors, 2022
Background Severe fever with thrombocytopenia syndrome (SFTS), caused by the SFTS virus (SFTSV), is an acute infectious disease transmitted by ticks that has recently been identified.
Xiao-Hu Han, Yue Ma, Hong-Yan Liu, Dan Li, Yan Wang, Feng-Hua Jiang, Qing-Tian Gao, Feng Jiang, Bao-Shan Liu, Guo-Shun Shen, Ze-Liang Chen   +10 more
doaj   +1 more source

Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome [PDF]

, 2016
Atypical hemolytic uremic syndrome (aHUS) is caused by alternative complement pathway dysregulation, leading to systemic thrombotic microangiopathy (TMA) and severe end-organ damage.
Al-Akash, Samhar I, Ardissino, Gianluigi, Bedrosian, Camille L, Evans, Jonathan, Fila, Marc, Greenbaum, Larry A, Henning, Paul, Licht, Christoph, Lieberman, Kenneth V, Maringhini, Silvio, Ogawa, Masayo, Pape, Lars, Rees, Lesley, van de Kar, Nicole CAJ, Vande Walle, Johan   +14 more
core   +2 more sources

Think highly of immunoglobulin G4‐related chronic rhinosinusitis as a clinical entity in immunoglobulin G4‐related disease

Eye &ENT Research, EarlyView.
Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan, Luo Zhang, Yingshi Piao, Yuan Zhang   +3 more
wiley   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source