Results 121 to 130 of about 37,883 (218)

Adding Bortezomib and Bendamustine to High‐Dose Melphalan in Autologous Haematopoietic Stem Cell Transplantation for Relapsed Multiple Myeloma—A Single Centre Retrospective Study

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction High‐dose melphalan (HDM) followed by autologous haematopoietic stem cell transplantation (ASCT) remains the standard of care for eligible patients with multiple myeloma (MM). Our objective was to evaluate the effectiveness and safety of adding bortezomib and bendamustine to melphalan (BBM) compared with HDM for relapsed MM, and ...
Thomas Silfverberg, Honar Cherif, Emma Smitt, Kristina Carlson   +3 more
wiley   +1 more source

Effects of Ribavirin on Severe Fever with Thrombocytopenia Syndrome Virus In Vitro

Japanese Journal of Infectious Diseases, 2014
Severe fever with thrombocytopenia syndrome (SFTS) is a disease with a high case fatality rate that is caused by infection with the recently identified tick-borne SFTS virus (SFTSV), for which there are no specific countermeasures. We examined the effects of ribavirin and mizoribine, which are nucleoside analogue drugs with broad antiviral activities ...
Masayuki, Shimojima, Shuetsu, Fukushi, Hideki, Tani, Tomoki, Yoshikawa, Aiko, Fukuma, Satoshi, Taniguchi, Yuto, Suda, Ken, Maeda, Toru, Takahashi, Shigeru, Morikawa, Masayuki, Saijo   +10 more
openaire   +3 more sources

Transmission of Severe Fever with Thrombocytopenia Syndrome (SFTS) to humans: A systematic review of individual participant data and meta-analysis

Journal of Infection and Public Health
Severe Fever with Thrombocytopenia Syndrome (SFTS) is a life-threatening emerging infectious disease caused by the SFTS virus. The aim of this systematic review and meta-analysis was to gain new insights into the routes of transmission to humans and ...
Darae Woo, Ian C. Michelow, Yongyeon Choi, Hyelan Lee, Sangshin Park   +4 more
doaj   +1 more source

N6-methyladenosine RNA modification promotes Severe Fever with Thrombocytopenia Syndrome Virus infection. [PDF]

PLoS Pathog
Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV), a novel bunyavirus primarily transmitted by Haemaphysalis longicornis, induces severe disease with a high mortality rate. N6-methyladenosine (m6A) is a prevalent internal chemical modification in eukaryotic mRNA that has been reported to regulate viral infection.
Chen Z, Zhang J, Wang J, Tong H, Pan W, Ma F, Wu Q, Dai J.   +7 more
europepmc   +4 more sources

A case of refractory thrombotic thrombocytopenic purpura treated with plasmapheresis and rituximab [PDF]

, 2016
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder with no prevalence or incidence studies in sub-Saharan Africa. Acquired TTP has several causes, all of which lead to decreased activity of von Willebrand factor cleaving ...
Kirui, Nicholas, Sokwala, Ahmed
core   +4 more sources

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Modeling Dengue Virus Infection Patients for Each Severity of Dengue Disease in Thailand [PDF]

, 2013
Dengue is an infectious mosquito-borne viral disease. Dengue or dengue-like epidemics ranks highly among new and newly emerging infectious diseases in public health significance and may affect persons of all ages in dengue endemic area.
O\u27Brien, Timothy, Tiensuwan, Montip
core  

Case report: detection of the identical virus in a patient presenting with severe fever with thrombocytopenia syndrome encephalopathy and the tick that bit her

BMC Infectious Diseases, 2018
Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease. Haemophysalis longicornis ticks have been considered the vector of severe fever with thrombocytopenia syndrome virus (SFTSV).
Uh. Jin Kim, Dong-Min Kim, Seong Eun Kim, Seung Ji Kang, Hee-Chang Jang, Kyung-Hwa Park, Sook In Jung   +6 more
doaj   +1 more source

Acute kidney injury and tools for risk-stratification in 456 patients with hantavirus-induced nephropathia epidemica [PDF]

, 2017
BACKGROUND Puumala virus (PUUV) is the most common species of hantavirus in Central Europe. Nephropathia epidemica (NE), caused by PUUV, is characterized by acute kidney injury (AKI) and thrombocytopenia.
Alscher, M Dominik, Braun, Niko, Brockmann, Stefan, Corea, Angela, Dippon, Juergen, Fritz, Peter, Gußmann, Karl, Hoffmann, Larissa, Kimmel, Martin, Kitterer, Daniel, Latus, Joerg, Mezger, Barbara, Müller, Simon, Pieper, Friedrich-Michael, Priwitzer, Martin, Pöhlmann, Christoph, Rettenmaier, Bianka, Schwab, Andrea, Schwab, Matthias, Segerer, Stephan, Tacconelli, Evelina, Walter-Frank, Birgit, Wegener, Daniel, Wiedenmann, Albrecht, Zakim, David   +24 more
core  

Development of a SFTSV DNA vaccine that confers complete protection against lethal infection in ferrets

Nature Communications, 2019
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus with no specific treatment or vaccine available. Here, the authors develop a DNA vaccine for SFTSV that is protective against lethal challenge in ferrets and show ...
Jeong-Eun Kwak, Young-Il Kim, Su-Jin Park, Min-Ah Yu, Hyeok-Il Kwon, Sukyeong Eo, Tae-Shin Kim, Joon Seok, Won-Suk Choi, Ju Hwan Jeong, Hyojin Lee, Youngran Cho, Jin Ah Kwon, Moonsup Jeong, Joel N. Maslow, Yong-Eun Kim, Haili Jeon, Kee K. Kim, Eui-Cheol Shin, Min-Suk Song, Jae U. Jung, Young Ki Choi, Su-Hyung Park   +22 more
doaj   +1 more source