Results 101 to 110 of about 37,883 (218)

2026 Update on the Management of Diffuse Large B‐Cell Lymphoma

American Journal of Hematology, Volume 101, Issue 4, Page 832-863, April 2026.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common type of NHL in the Western Hemisphere. It comprises a heterogenous group of lymphomas, with different biology and clinical prognoses. R‐CHP remains the backbone of therapy, and frontline therapeutic options in fit patients are pola‐R‐CHP and R‐CHOP, whereas elderly or frail/unfit ...
Elise A. Chong, Emily B. Tomasulo, Stefan K. Barta   +2 more
wiley   +1 more source

Therapeutic efficacy of favipiravir against Bourbon virus in mice [PDF]

, 2019
Bourbon virus (BRBV) is an emerging tick-borne RNA virus in the orthomyxoviridae family that was discovered in 2014. Although fatal human cases of BRBV have been described, little is known about its pathogenesis, and no antiviral therapies or vaccines ...
Bailey, Thomas, Boon, Adrianus C. M., Bricker, Traci L, Diamond, Michael S, Gounder, Anshu P, Jagger, Brett W, Janowski, Andrew B, Kwon, Jennie H, Shafiuddin, Md., Wang, David, Williams, Graham D, Zhao, Guoyan   +11 more
core   +3 more sources

Efficacy and Safety of Intensity‐Modulated Radiotherapy Combined With Regorafenib With or Without Immune Checkpoint Inhibitors as Second‐Line Treatment for Advanced Hepatocellular Carcinoma: A Real‐World Cohort Study From a Single Center

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Purpose This study aimed to assess the efficacy and safety of intensity‐modulated radiotherapy (IMRT) combined with regorafenib with or without immune checkpoint inhibitors (ICIs) as a second‐ or later‐line treatment for advanced hepatocellular carcinoma (HCC).
Lingxia Xin, Zhiyu Li, Yirui Zhai, Liming Wang, Feng Ye, Yongkun Sun, Wen Zhang, Tiago Biachi de Castria, Sanjaya K. Satapathy, Vishal G. Shelat, Shaffer R. S. Mok, Jennifer Wu, Shulian Wang, Yueping Liu, Yongwen Song, Yuan Tang, Hao Jing, Hui Fang, Shunan Qi, Ningning Lu, Ye‐Xiong Li, Xinyu Bi, Bo Chen   +22 more
wiley   +1 more source

Longitudinal Monitoring of GRIm and HCC‐GRIm Scores Reveals Immunologically Relevant Prognostic Indicators in Hepatocellular Carcinoma Undergoing TACE Plus ICIs and Anti‐VEGF Antibodies/TKIs

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Objective To investigate the clinical significance and peripheral immunological basis underlying the dynamic changes of Gustave Roussy Immune (GRIm) score and the hepatocellular carcinoma‐specific GRIm (HCC‐GRIm) score in unresectable hepatocellular carcinoma (uHCC) patients treated with transarterial chemoembolization (TACE) combined with ...
Lihao Qin, Linzhou Zhu, Yu Wang, Wanci Li, Shuai Zhang, Jian Shen, Xiaoli Zhu   +6 more
wiley   +1 more source

Early Tick Species Identification Using Eschar‐Based PCR to Guide Presymptomatic Risk Assessment in Tick‐Borne Diseases

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT In endemic regions where simultaneous larval tick bites frequently occur, early identification of tick species from eschar lesions may substantially influence presymptomatic clinical triage. We report a 78‐year‐old woman who was found after approximately 24 h of wandering, presenting with multiple clustered eschars on the lower extremities and
Makoto Kondo, Koji Habe, Keiichi Yamanaka   +2 more
wiley   +1 more source

Proven invasive pulmonary aspergillosis in the early clinical course of severe fever with thrombocytopenia syndrome: Importance of an early diagnosis

Journal of Microbiology, Immunology and Infection, 2021
Gil Myeong Seong, Jeong Rae Yoo, Joong-Goo Kim, Chang Lim Hyun, Misun Kim, Hyun Joo Oh, Keun Hwa Lee   +6 more
doaj   +1 more source

Unusual case of severe fever with thrombocytopenia syndrome showing clinical manifestations in a companion dog

Veterinary Medicine and Science, 2020
Severe fever with thrombocytopenia syndrome (SFTS) virus is an emerging zoonotic virus in East Asia. However, SFTS virus (SFTSV) has not been reported to cause clinical infection in companion dogs to date. We report the case of a 4‐year‐old companion dog
So‐Jeong Nam, Ye‐In Oh, Hyun‐Jung Kim, Doo‐Sung Cheon, Sung‐Jun Noh, Yeon‐Jung Hong   +5 more
doaj   +1 more source

Leucoreduction of blood components. an effective way to increase blood safety? [PDF]

, 2015
Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens
Bianchi, Maria, Facco, Giuseppina, Grazzini, Giuliano, Liumbruno, Giancarlo M, Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +6 more
core   +1 more source

Utility of Patch Testing, LTT, and HLA Genotyping in Identifying Culprit Drugs and Diagnosing Multiple Drug Hypersensitivity in Definite DRESS: A 10‐Year Cohort Study

Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.
In a prospective cohort of patients with definite Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), multiple drug hypersensitivity syndrome (MDHS) was associated with increased disease severity and a higher frequency of human leukocyte antigen (HLA) risk alleles.
Derya Ünal, Osman Ozan Yeğit, Semra Demir, Bircan Erden, Pelin Korkmaz, Fatma Savran Oğuz, Çiğdem Kekik Çınar, Sonay Temurhan, Deniz Eyice Karabacak, Ilkim Deniz Toprak, Zeynep Kılınç, Mehmet Sait Yordam, Nevzat Kahveci, Merve Hörmet İğde, Şule Çelik Kamacı, Ayşe Feyza Aslan, Mehmet Emin Sezgin, Esra Kaya, Leyla Bölek, Raif Coşkun, Müge Olgaç, Nida Öztop, Aslı Gelincik   +22 more
wiley   +1 more source

Severe Fever with Thrombocytopenia Syndrome Virus, Crimean-Congo Haemorrhagic Fever Virus, and Migratory Birds

Journal of Bacteriology and Virology, 2013
Severe Fever with Thrombocytopenia Syndrome (SFTS) and Crimean-Congo Haemorrhagic Fever (CCHF) are tick-borne diseases belonging to the family Bunyaviridae. Since SFTS was first reported in China in 2009, the virus was isolated and confirmed in 2011, with additional reports of SFTSV expanding its geographic range from China to South Korea and Japan ...
Keun Hwa Lee, Jolyon M. Medlock, Sang Taek Heo   +2 more
openaire   +1 more source