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Hypoglycemia is an often-observed acute complication in the management of children and adolescents with type 1 diabetes. It causes inappropriate glycemic outcomes and may impair the quality of life in the patients.
Tatsuhiko Urakami
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Severe Hypoglycemia Caused by Lenalidomide
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2017Lenalidomide is commonly used for multiple myeloma as either induction or maintenance therapy. The agent is associated with a host of adverse effects, but hypoglycemia has only been reported in one phase I trial in patients with solid tumors. We describe a 74‐year‐old woman who experienced grade 3 hypoglycemia (blood glucose level 35 mg/dl) likely ...
Daniel J. Przybylski +2 more
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Severe Hypoglycemia and Vulnerability of the Brain
Archives of Neurology, 2006A N 82-YEAR-OLD WOMAN PRESENTED TO THE emergency department with altered mental status. Her son had conversed with her by telephone 36 hours before the onset, but he could not reach her by telephone 24 hours after that. She had a medical history of right hemiparesis and dysarthria 14 years earlier and had been taking medication for hypertension as well
Soo-Jin, Cho +2 more
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Dasiglucagon: an effective medicine for severe hypoglycemia
European Journal of Clinical Pharmacology, 2021Patients with type 1 diabetes mellitus (T1DM) receiving insulin therapy commonly suffer from insulin-mediated hypoglycemia and require glucagon for glycemic control to achieve normal plasma glucose (PG) levels. Severe hypoglycemia will endanger the life of patients and require intervention.
Bo Xu, Gaorui Tang, Zhen Chen
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Severe Hypoglycemia in IDDM Children
Diabetes Care, 1989The incidence of severe hypoglycemia was determined in a 1-yr prospective study of 350 insulin-dependent diabetic (IDDM) children. There were no significant differences in mean glycosylated hemoglobin, age, and duration of disease between the patients who had severe hypoglycemia and those who did not. There were 25 episodes in 24 patients (6.8%). Their
I, Bergada +3 more
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Unusual Presentation of Severe Hypoglycemia
American Journal of Clinical Pathology, 1980An unusual case of severe hypoglycemia during which a patient was awake and able to walk despite a serum glucose concentration of 10 mg/dl (0.55 mmol/l) is reported. No tumor was found at autopsy, and the patient was not diabetic. Repeat glucose determinations on the initial as well as subsequent blood samples and a mixing study were performed to ...
S C, Hansen, H, Simpkins
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SEVERE POSTOPERATIVE HYPOGLYCEMIA
Journal of the American Medical Association, 1946The clinical state associated with hypoglycemia is assuming an increasing importance in the differential diagnosis of atypical nervous system reactions. Since the first description of this condition by Harris1in 1924 there has developed a large body of literature pertaining in particular to etiologic mechanisms.
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Archives of Internal Medicine, 1965
MOST reported side effects of chlorpropamide are transient and dose-related. Occasionally, severe toxicity involving the liver, skin, bone marrow, and gastrointestinal tract occurs. 1 Hypoglycemic complaints are usually minor, and coma is rare if the drug is given in recommended doses.
E L, ROTHFELD +3 more
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MOST reported side effects of chlorpropamide are transient and dose-related. Occasionally, severe toxicity involving the liver, skin, bone marrow, and gastrointestinal tract occurs. 1 Hypoglycemic complaints are usually minor, and coma is rare if the drug is given in recommended doses.
E L, ROTHFELD +3 more
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Biopsychobehavioral model of severe hypoglycemia. II. Understanding the risk of severe hypoglycemia.
Diabetes Care, 1999OBJECTIVE: To evaluate the clinical/research utility of the biopsycho-behavioral model of severe hypoglycemia in differentiating patients with and without a history of severe hypoglycemia and in predicting occurrence of future severe hypoglycemia. RESEARCH DESIGN AND METHODS: A total of 93 adults with type 1 diabetes (mean age 35.8 years, duration of ...
D J, Cox +6 more
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Hunting for a hypoglycemia gene: Severe neonatal hypoglycemia in a consanguineous family
American Journal of Medical Genetics, 2002AbstractHypoglycemia is a dreaded complication in diabetes mellitus patients treated with insulin, but is also a symptom that is observed in many disorders. In some metabolic diseases of early infancy, low blood glucose is the major presentation and the condition can become life‐threatening. Such cases are often attributed to inherited hyperinsulinism.
Anders, Molven +4 more
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