Results 101 to 110 of about 2,972,520 (248)

Brainstem anaesthesia after retrobulbar block

Open Medicine, 2019
Regional anaesthesia techniques in ophthalmology are usually utilized for day case surgery. During various procedures, profound akinesia of the eye and anaesthesia of the surgical site are required, both of which are achieved with retrobulbar block.
Kostadinov Ivan, Hostnik Andrej, Cvenkel Barbara, Potočnik Iztok   +3 more
doaj   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source

Lost Circulation and Wellbore Strengthening [electronic resource] /

This book focuses on the underlying mechanisms of lost circulation and wellbore strengthening, presenting a comprehensive, yet concise, overview of the fundamental studies on lost circulation and wellbore strengthening in the oil and gas industry, as ...
Feng, Yongcun.author.authttp://id.loc.gov/vocabulary/relators/aut, Gray, K. E.author.authttp://id.loc.gov/vocabulary/relators/aut, SpringerLink (Online service)   +2 more
core   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Preparation and Physicochemical Properties of High-Temperature-Resistant Polymer Gel Resin Composite Plugging Material

Gels
Lost circulation has become one of the important problems restricting the speed and efficiency of oil and gas drilling and production. To address severe drilling fluid losses in high-temperature fractured formations during deep/ultra-deep well drilling ...
Tao Wang, Weian Huang, Jinzhi Zhu, Chengli Li, Guochuan Qin, Haiying Lu   +5 more
doaj   +1 more source

Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

Advanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai, Liang Zhang, Wenxin Tao, Jieyuan An, Lantian Wang, Zhaoyou Liu, Guodong Yang, Pengying Wu, Lijun Yuan   +8 more
wiley   +1 more source

Decoding the evolutionary history of ST30 Staphylococcus aureus: insights into a potentially silent MSSA bloodstream pathogen

Frontiers in Microbiology
BackgroundStaphylococcus aureus clonal complex 30 (CC30) is a historically significant pathogen affecting both hospital and community settings. The notable pandemic clones, phage-type 80/81 (PT80/81) and the Southwest Pacific clone (SWP) have spread ...
Matheus Assis Côrtes Esteves, Mariana Fernandes Carvalho, Alice Slotfeldt Viana, Caroline Lopes Martini, Luis Guilherme Araújo Longo, Luis Guilherme Araújo Longo, Deborah Nascimento Santos Silva, Adriana Lucia Pires Ferreira, Bernadete Teixeira Ferreira-Carvalho, Paul Joseph Planet, Paul Joseph Planet, Agnes Marie Sá Figueiredo, Agnes Marie Sá Figueiredo   +12 more
doaj   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Floods of Egypt’s Nile in the 21st century

Scientific Reports
Extreme precipitation and flooding events are rising globally, necessitating a thorough understanding and sustainable management of water resources. One such setting is the Nile River’s source areas, where high precipitation has led to the filling of ...
Ahmed Badawy, Mohamed Sultan, Karem Abdelmohsen, Eugene Yan, Hesham Elhaddad, Adam Milewski, Hugo E. Torres-Uribe   +6 more
doaj   +1 more source

Thirsty Reservoirs - Challenges in Drilling Through Severe Lost Circulation Zones

, 2017
In this paper, we present a thorough analysis of drilling methods and fluid and mechanical solutions to mitigate lost circulation (LC), as well as risk control measures undertaken, while drilling 5 wells on two platforms with severe LC zones in the ...
Chinthaka P. Gooneratne, Abdulaziz S. Al-Musa, Hugo F. Osorio, Ernesto S. Gomez Gonzalez   +3 more
core   +1 more source