Results 231 to 240 of about 1,804,243 (315)

Plasmodium falciparum Parasites With Histidine‐Rich Protein 2 (pfhrp2) and pfhrp3 Gene Deletions in Frontier Endemic Regions of Brazilian Amazon

Tropical Medicine &International Health, EarlyView.
ABSTRACT Studies reporting deletions of the pfhrp2 and pfhrp3 genes in P. falciparum populations in various malaria‐endemic countries, including countries bordering Brazil, are increasing. Individuals infected with P. falciparum carrying deletions of the pfhrp2/3 genes may yield false‐negative results in Rapid Diagnostic Tests (RDTs) based on the ...
Jéssica de Oliveira Bonsanto Gonçalves, Simone da Silva Santos, Rodrigo Medeiros Martorano, Jaime Louzada, Victoria Martins Roque Almeida, Lucas Rego Viana, Josely Oliveira Ferreira, Anielle Pina Costa, André Siqueira, Martha Cecília Suárez‐Mutis   +9 more
wiley   +1 more source

Sevuparin in children with severe malaria: A phase I safety and dose finding trial

Maitland K, Chaponda M, Gwasupika J, Kabwit PT, Miti S, Connon R, Gibb D, Walker AS, George E, williams T, Obonyo N, Day NP, Dondorp A.   +12 more
europepmc   +1 more source

Prevalence and risk factors of gross neurologic deficits in children after severe malaria: A systematic review and meta-analysis. [PDF]

PLoS One
Okullo AE, Ouma S, John CC, van Hensbroek MB, Ojiambo KO, Otike C, Kinengyere AA, Conroy AL, Ocan M, Obuku EA, Idro R.   +10 more
europepmc   +1 more source

Molecular characterization of CD36 deficiency in blood donors of Middle Eastern and African origin reveals transcript‐level defects beyond genomic variants

Transfusion, EarlyView.
Abstract Background The increasing diversity of blood donor populations has created new challenges for transfusion services worldwide. The identification of donors lacking relevant high‐prevalence antigens is becoming increasingly important to ensure compatible blood products for alloimmunized patients and to support the development of rare donor ...
Sarah Petermann, Inga Stellmacher, Brigitte K. Flesch, Tanja Rehling, Irina Häcker, Marc F. Schetelig, Alexander Carbol, Lambros Kordelas   +7 more
wiley   +1 more source

Symmetrical lower extremity gangrene in a patient with severe malaria: a case report and literature review. [PDF]

IDCases
Aman ST, Belay EH, Jirata TD, Hussen SH, Isa SF, Abagojam AH, Kebede ML, Bezabih KT, Tukeni KN.   +8 more
europepmc   +1 more source

Budget impact of implementing universal Plasmodium NAT screening in the blood transfusion system in the US

Transfusion, EarlyView.
Abstract Background Blood donor deferral for malaria risk relies exclusively on responses to self‐reported questionnaires. This study evaluated the economic impact of introducing Plasmodium nucleic acid testing (NAT) as a universal screening strategy in the United States.
Cristina Coll‐Ortega, Elisabet Viayna, Jiani Zhou, Susan L. Stramer   +3 more
wiley   +1 more source

The Management of Severe Falciparum Malaria

American Journal of Respiratory and Critical Care Medicine, 2003
openaire   +3 more sources

Facilitators and barriers to adherence to severe malaria treatment guidelines in children at Mbale Regional Referral Hospital, Uganda: a health workers' perspective. [PDF]

Malar J
Chelangat SC, Nakawuki A, Orech S, Oboth P, Nekaka R, Iramiot JS, Mbwali I, Chalo RN, Epuitai J, Adongo PR, Ssenyonga LVN, Olowo S.   +11 more
europepmc   +1 more source

Autoantibodies to Extracellular Erythrocyte Band 3 Epitopes Are Associated With Anemia in Plasmodium vivax Infection

American Journal of Hematology, Volume 101, Issue 10, Page 2592-2604, October 2026.
ABSTRACT Plasmodium vivax‐associated anemia is a multifactorial clinical outcome, in which the destruction of uninfected red blood cells (uRBCs) plays a major role in disease development and severity. Here, we identified autoantibody targets within the extracellular loops of Band 3 (B3), a major erythrocyte transmembrane protein.
Aline Marzano‐Miranda, Vanessa G. Fraga, Cor Jésus F. Fontes, Simone Ladeia‐Andrade, Marcelo U. Ferreira, Daniella C. Bartholomeu, Érika M. Braga   +6 more
wiley   +1 more source

Developmental Toxicity Study for the Antimalarial Drug Combination Cabamiquine‐Pyronaridine Using a Translational Approach

Birth Defects Research, Volume 118, Issue 10, October 2026.
ABSTRACT Background The safety of pharmacological treatments during pregnancy is a significant concern, as many medications lack comprehensive reproductive safety data. This creates gaps in therapeutic options for pregnant women, particularly malaria, which poses serious risks to maternal and fetal health.
Wookyung Kim, Geum‐Sil Cho, Andreas Gado, Tobias Hyun Ho Baeurle, Habib Karimi, Filippo Venezia, Claude Oeuvray, Thomas Spangenberg, Sebastian G. Wicha, Claudia Demarta‐Gatsi   +9 more
wiley   +1 more source