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COSSMaT Study: Protocol for Developing a Core Outcome Set for Severe Malaria Treatment Trials
Asamoah GD +4 more
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Infection, 2019
Malaria represents a medical emergency. Without rapid diagnosis and treatment, it can progress and lead to severe complications and, eventually, death. Severe malaria is almost always caused by Plasmodium falciparum. Here, we present an image showing a set of hematological findings associated with severe malaria, highlighting the importance of a ...
Marco P. Barros Pinto +1 more
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Malaria represents a medical emergency. Without rapid diagnosis and treatment, it can progress and lead to severe complications and, eventually, death. Severe malaria is almost always caused by Plasmodium falciparum. Here, we present an image showing a set of hematological findings associated with severe malaria, highlighting the importance of a ...
Marco P. Barros Pinto +1 more
openaire +2 more sources
Severe hyponatraemia in malaria
Journal of Infection, 1991We report a case of severe hyponatraemia and hypoglycaemia in a patient with complicated falciparum malaria. The use of large volumes of intravenous dextrose as a diluent for quinine may lead to fluid overload and exacerbate hyponatraemia.
S H, Khoo, E G, Wilkins
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The Indian Journal of Pediatrics, 2004
Falciparum malaria affect all ages with multiple-systemic complications which varies in different age group. We studied 242 children with complicated Falciparum malaria with a median age of 6.5 years to look for occurrence of different complications in younger and older age groups and overall mortality picture.
S K, Satpathy +3 more
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Falciparum malaria affect all ages with multiple-systemic complications which varies in different age group. We studied 242 children with complicated Falciparum malaria with a median age of 6.5 years to look for occurrence of different complications in younger and older age groups and overall mortality picture.
S K, Satpathy +3 more
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The Microcirculation in Severe Malaria
Microcirculation, 2004ABSTRACTSevere malaria in humans and animals is initiated by interactions between malaria‐infected cells, host blood cells (including monocytes, T cells and platelets) and endothelial cells of the microcirculation. Adhesion to vascular cells, and possible vascular obstruction in severe human disease, involves interaction between host receptors and ...
Stephen J, Rogerson +2 more
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The Indian Journal of Pediatrics, 2004
Prompt diagnosis and early institution of therapy is an important determinant of outcome in severe falciparum malaria. Thick smears are the gold standard for diagnosis; in situations where reliable microscopy is not available, tests based on HRP-2 antigen/parasite LDH are useful. As there is widespread resistance to chloroquine in P falciparum in India,
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Prompt diagnosis and early institution of therapy is an important determinant of outcome in severe falciparum malaria. Thick smears are the gold standard for diagnosis; in situations where reliable microscopy is not available, tests based on HRP-2 antigen/parasite LDH are useful. As there is widespread resistance to chloroquine in P falciparum in India,
openaire +2 more sources
Hypoglycaemia in severe falciparum malaria
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988The incidence of hypoglycaemia and the role of quinine in its causation was assessed in 46 patients with severe Plasmodium falciparum malaria. Plasma glucose and immunoreactive insulin were estimated before, during and after quinine therapy. In 5 patients the plasma glucose was in the hypoglycaemic range, the lowest value being 0.67 mmol/litre (12 mg ...
B S, Das +7 more
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ICU management of severe malaria
The Indian Journal of Pediatrics, 2001Malaria is very common in India. First step in management of malaria is to establish the diagnosis. It is established by using traditional smear or method like dipstick antigen captures assay which is simpler, accurate and doesn't require expertise. Next step is to look for signs and symptoms, which help cases of severe malaria should be admitted in ...
D, Gupta, K, Chugh, A, Sachdev, A, Soni
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Hyperkalemia in Pediatric Severe Malaria
Seminars in NephrologySevere malaria remains an important global cause of mortality, particularly in sub-Saharan Africa, where the majority of deaths occur in children under 5 years of age. Hyperkalemia in severe malaria has not been very well reported but is associated with increased mortality.
Michael, Lintner-Rivera +5 more
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