Results 71 to 80 of about 3,799,152 (295)

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Violent victimization of adult patients with severe mental illness: a systematic review

Neuropsychiatric Disease and Treatment, 2014
Klara Latalova,1,2 Dana Kamaradova,1,2 Jan Prasko1,2 1Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic; 2Department of Psychiatry, University Hospital Olomouc, Olomouc, Czech Republic Abstract: The aims of this ...
Latalova K, Kamaradova D, Prasko J
doaj  

The development and validation of a medicines optimisation tool to protect the physical health of people with severe mental illness (OPTIMISE)

BMC Psychiatry, 2022
Background The life expectancy of people with severe mental illness (SMI) is shorter than those without SMI, with multimorbidity and poorer physical health contributing to health inequality.
Aoife Carolan, Dolores Keating, Stephen McWilliams, Caroline Hynes, Mary O’Neill, Fiona Boland, Sharon Holland, Judith Strawbridge, Cristín Ryan   +8 more
doaj   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Barriers and facilitators to social inclusion among people with severe mental illness: A qualitative study.

PLOS Mental Health
People with severe mental illness are often socially excluded. Social exclusion is associated with worse mental health outcomes and poorer quality of life, making it a key target for recovery.
Sharon Eager, Brynmor Lloyd-Evans, Jennifer Bousfield, Joanna C, Megan Downey, Isobel Harrison, Helen Killaspy, Gillian Mezey   +7 more
doaj   +1 more source

An Interpretable, Data‐Driven, Hierarchical Multi‐Domain Fusion Framework for Classification and Motor Function Scoring in Chronic Ankle Instability

Advanced Science, EarlyView.
An AI‐enabled digital twin framework integrates wearable EMG sensing with hierarchical multi‐domain fusion to classify chronic ankle instability, distinguish clinically relevant subtypes, and generate continuous motor function scores. Clinically interpretable functional stratification and SHAP‐based biomarker analysis provide transparent decision ...
Tianle Jie, Datao Xu, Zhifeng Zhou, Bas Van Hooren, Huiyu Zhou, Yi Yuan, Xiangli Gao, Monèm Jemni, Liangliang Xiang, Meizi Wang, Justin Fernandez, Tibor J. Goda, Yaodong Gu   +12 more
wiley   +1 more source

Emotional and behavioural symptoms in childhood (aged 8–14) and severity of mental illness outcomes in young adults: a retrospective observational study using cross-sectional data from electronic health records in the clinical practice research datalink (CPRD)

BMC Pediatrics
Background This study aimed to investigate the prevalence and impact of emotional and behavioural dysregulation (EBD) symptoms in childhood/early adolescence reported in primary care among young adults with severe mental illness.
Ana Pascual-Sanchez, Geva Greenfield, Hanna-Marie Creese, Sonia Saxena, Dougal Hargreaves, Dasha Nicholls   +5 more
doaj   +1 more source

Analysis of differences regard to use, knowledge, interest and attitudes towards new information technologies between people with and without severe mental disorders

INFAD, 2017
This article compares people with severe mental disorders and people without mental disorders regard to use, knowledge, interest and attitudes towards new information technologies (ICT). In the study participated seven persons with severe mental illness,
Carla Natalia Casiano Yanicelli, María Carmen Lozano Segura, Cristian Aguilera Ruiz, Ana Manzano León   +3 more
doaj   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Contraceptive use among women with severe mental illness at Gulu Regional Referral Hospital in Northern Uganda

Women's Health
Background: Severe mental illness influences uptake of contraceptive services through a number of factors in developing countries including Uganda. The paucity of data on contraceptive use among females with severe mental illness in sub-Saharan Africa ...
Betijuma Luwedde, Bives Mutume Nzanzu Vivalya, Joshua Muyomba, Mpamizo Emmanuel   +3 more
doaj   +1 more source