Results 51 to 60 of about 759,666 (309)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Illness management and recovery (IMR) in Danish community mental health centres [PDF]

, 2011
Background: Schizophrenia and bipolar disorder are severe mental illnesses that can have a significant disabling impact on the lives of people. Psychosocial interventions that stress hope and recovery as a part of a multidimensionalapproach are possibly ...
Helle Stentoft Dalum, Jane Lindschou Hansen, John Hagel Mikkelsen, Karin Thomsen, Kristen Kistrup, Lene Falgaard Eplov, Lisa Korsbek, Merete Nordentoft, Mette Olander   +8 more
core   +3 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Exploring Gender Differences in Quality of Life [PDF]

, 2012
Purpose – The purpose of this study is to examine gender differences with regard to physical activity, psychiatric symptoms, and quality of life in patients with severe mental illness.
Bonsaksen, Tore
core   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Holistic healing for hearing voices: self-care for patients with schizophrenia [PDF]

, 2017
Schizophrenia is one of the more severe mental illnesses which poses immense costs to societies and patients. Worldwide it is believed that about 52 million individuals suffer from this illness.
Beyer, Anna Cornelia
core  

Impact of socioeconomic deprivation on rate and cause of death in severe mental illness [PDF]

, 2014
Background: Socioeconomic status has important associations with disease-specific mortality in the general population. Although individuals with Severe Mental Illnesses (SMI) experience significant premature mortality, the relationship between ...
AC Phillips, AJ Kposowa, AP Weiss, B Schneider, C Crump, C-K Chang, CW Colton, D Lawrence, D Osborn, DA Regier, Daniel J Martin, Daniel J Smith, DJ Gunnell, DJ Smith, DJ Smith, DN Baxter, DP Osborn, E Scafato, E Tran, E Van Doorslaer, G McCartney, Gary McLean, GK Singh, I Stirbu, J Park, John Park, Julie Langan Martin, K Barnett, K Hawton, K Wahlbeck, M DE Hert, Moira Connolly, NE Morden, P Congdon, PG Surtees, R Taylor, RA Payne, S Aro, S Oksbjerg Dalton, S Strickland, SD Rosenberg, SM Frayne, Stewart W Mercer, TJ Lambert, TM Laursen, TM Laursen, U Hoang, VS Catts   +47 more
core   +2 more sources

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Why do Patients with Severe Mental Illness Smoke Cigarettes?

Translation
The disparity in rates of cigarette smoking between patients with severe mental illnesses (SMIs) and the general population is a well-documented phenomenon.
Paige Nicole Prologo-Richardson, David Michael Paternite, Emma Wolinsky, Mark Houdi, Jacob Schmieder, Catherine Howell, Alyssa Davis, Britta Eldridge, Charlotte Lennox, Carly Kelley, Jamie Dowling, Chandani Lewis   +11 more
doaj   +1 more source

Post traumatic stress disorder symptoms and stress burden among caregivers of patients with severe mental illness

European Psychiatry, 2021
Introduction Care givers of patients with severe mental disorders have been shown to be under heavy stress burden that reflect itself through various heterogenous psychiatric symptoms that may mimic PTSD with associated negative impact on interpersonal
A. Rady, T. Mouloukheya, E. Ramadan
doaj   +1 more source