Genetics of Severe Obesity [PDF]
Current Diabetes Reports, 2018 Purpose of Review This review aims to present current information on genes underlying severe obesity, with the main emphasis on the three genes LEP, LEPR and MC4R.
Fairbrother, U +3 more
core +5 more sources
Assessing Hepatic Steatosis Following Weight Loss in Adolescents with Severe Obesity: A Randomized Controlled Trial [PDF]
ChildrenBackground/Objectives: To assess whether laparoscopic adjustable gastric banding (LAGB) and combined lifestyle intervention (CLI) reduce hepatic steatosis more effectively than CLI alone in adolescents with severe obesity. Methods: Adolescents aged 14–16
Ali Talib +8 more
doaj +2 more sources
Severe obesity with hypo-leptinemia. [PDF]
Endocr JSome cases of obesity are thought to be associated with hypo-leptinemia. This may cause decreased appetite suppression resulting in increased appetite, leading to weight gain. Replacement therapy with leptin might be theoretically useful, but verification by reporting more cases is required. Here, we first investigated the serum leptin levels and their
Kita M +7 more
europepmc +4 more sources
Serum leptin and its relation to body composition, puberty, and metabolism in severe obesity [PDF]
Endocrine ConnectionsChildhood severe obesity (SO) is a growing public health concern. Leptin (LEP) and its biologically active fraction (BioLEP) play a key role in energy balance and body mass regulation.
Sabina Galiniak +15 more
doaj +2 more sources
Trends in the Prevalence of Overweight, Obesity and Severe Obesity in Primary School Children in Croatia from 2003 to 2022 [PDF]
ChildrenBackground: Childhood obesity remains a significant public health challenge globally. Croatia ranks among the leading European countries in terms of childhood overweight and obesity prevalence.
Sanja Musić Milanović +5 more
doaj +2 more sources
Altered Spontaneous Brain Activity Patterns of Meibomian Gland Dysfunction in Severely Obese Population Measured Using the Fractional Amplitude of Low-Frequency Fluctuations [PDF]
Frontiers in Psychiatry, 2022 ObjectiveUtilizing the fractional amplitude of low-frequency fluctuations (fALFF) technique, this study sought to correlate spontaneous cerebral abnormalities with the clinical manifestations of meibomian gland dysfunction (MGD) in severely obese (SO ...
Yu-Ling Xu +11 more
doaj +2 more sources
The effect of probiotics on weight management in patients with severe obesity undergoing metabolic and bariatric surgery: a systematic review and meta-analysis [PDF]
Annals of MedicineBackground Although metabolic and bariatric surgery (MBS) remains an effective intervention for severe obesity, postoperative weight regain persists as a significant clinical challenge.
Shi Wang +5 more
doaj +2 more sources
Biomedicines, 2023 Background: Weight loss before undergoing metabolic and bariatric surgery (MBS) has been suggested to reduce perioperative complications, although with controversial results.
Miguel A. Rubio-Herrera +3 more
doaj +1 more source
Brain Sciences, 2021 Visceral adipose tissue accumulation is an important determinant of metabolic risk and can be estimated by the visceral adiposity index (VAI). Visceral adiposity may impact brain regions involved in eating behavior.
Sylvain Iceta +9 more
doaj +1 more source
Frontiers in Human Neuroscience, 2022 PurposeTo evaluate potential regional homogeneity (ReHo) cerebrum function lesions in people with severe obesity and meibomian gland dysfunction (SM) and probe the connection between aberrant cerebrum activity and clinical manifestations.Patients and ...
Yi Liu +9 more
doaj +1 more source