Results 61 to 70 of about 628,141 (359)

Severe Obesity Hypoventilation Syndrome Treated with Auto-CPAP [PDF]

, 2016
Summary Obesity hypoventilation syndrome (OHS) is a serious medical condition that remains undiagnosed in seriously ill hospitalized patients. Significant improvement of daytime hypercapnia can be achieved with positive airway pressure (PAP) therapy. Bi-
Fast, MD, Zhanna, Grewal, MD, Ritu G.
core   +1 more source

Disadvantaged children at greater relative risk of thinness (as well as obesity): a secondary data analysis of the England National Child Measurement Programme and the UK Millennium Cohort Study [PDF]

, 2015
Introduction: Young children living in more disadvantaged socio-economic circumstances (SECs) are at an increased risk of overweight and obesity. However, there is scant research examining the prevalence and social distribution of thinness in early ...
Law, Catherine, Pearce, Anna, Rougeaux, Emeline   +2 more
core   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Psychological symptoms in obesity and related factors [PDF]

, 2015
Introduction: This study aimed to investigate the relationship between levels of depression and anxiety symptoms and quality of life, self-esteem in obesity.
Değirmenci, T., Fenkçi, S., Kalkan Oğuzhanoğlu, Nazan, Sözeri-Varma, G., Özdel, O.   +4 more
core   +1 more source

Eating behaviours are different in youth with obesity and severe obesity [PDF]

Clinical Obesity, 2015
SummaryThe study purposes were to: (i) Investigate eating behaviours among patients in a paediatric weight management clinical practice and (ii) Compare eating behaviour phenotypes between children with severe obesity and obesity. This was a retrospective cross‐sectional study using data collected during clinical encounters.
Allison M. H. Foy, Aaron S. Kelly, Amy C. Gross, Kyle Rudser, Claudia K. Fox   +4 more
openaire   +3 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study [PDF]

, 2017
Obesity is an independent risk factor for chronic breathlessness and should be assessed in people with this ...
Currow, David C., Dal Grande, Eleonora, Ekström, Magnus, Johnson, Miriam J., Sidhu, Calvin   +4 more
core   +2 more sources

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Short report: Pancreatic dysfunction in severe obesity [PDF]

Archives of Disease in Childhood, 2001
To investigate pancreatic function in children attending an obesity clinic.Thirty six children (of which 34 were white) with severe obesity of prepubertal onset (body mass index more than +2 SDS) were reviewed clinically and dysmorphologically, with assessment of pancreatic function.Eight had dysmorphic features and 13 had learning difficulties.
Elizabeth Crowne, Ruth Newbury-Ecob, Julian P.H. Shield, Amanda Drake, L Greenhalgh   +4 more
openaire   +3 more sources

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source