Results 71 to 80 of about 2,020,313 (253)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Severe obesity with hypo-leptinemia

Endocrine Journal
Some cases of obesity are thought to be associated with hypo-leptinemia. This may cause decreased appetite suppression resulting in increased appetite, leading to weight gain. Replacement therapy with leptin might be theoretically useful, but verification by reporting more cases is required. Here, we first investigated the serum leptin levels and their
Kita, Masanori, Morita, Shuhei, Ariyasu, Hiroyuki, Tsuji, Tomoya, Uraki, Shinsuke, Takeshima, Ken, Iwakura, Hiroshi, Matsuoka, Taka-aki   +7 more
openaire   +3 more sources

The role of nitro oxidative factors in metabolic dysfunctions: A link between severe obesity and weight-loss treatment – a narrative review

Romanian Journal of Laboratory Medicine
Introduction: Metabolic syndrome (MS) is linked to oxidative stress and intracellular redox imbalance, both triggered by chronic inflammatory conditions.
Ion Razvan Marius, Sibianu Melania, Neagoe Radu, Sala Daniela, Beresescu Felicia, Daniealopol Valentin, Daniealopol Ruxandra, Muresan Mircea   +7 more
doaj   +1 more source

Novel Mutations in Obesity-related Genes in Turkish Children with Non-syndromic Early Onset Severe Obesity: A Multicentre Study

JCRPE, 2019
Objective:Non syndromic monogenic obesity is a rare cause of early onset severe obesity in the childhood period. This form may not be distinguishable from other forms of severe obesity without genetic analysis, particularly if patients do not exibit any ...
Ayşehan Akıncı, Doğa Türkkahraman, İbrahim Tekedereli, Leyla Özer, Bahri Evren, İbrahim Şahin, Tarkan Kalkan, Yusuf Çürek, Emine Çamtosun, Esra Döğer, Aysun Bideci, Ayla Güven, Erdal Eren, Özlem Sangün, Atilla Çayır, Pelin Bilir, Ayça Törel Ergür, Oya Ercan   +17 more
doaj   +1 more source

The public health impact of obesity [PDF]

, 2001
The prevalence of obesity (severe overweight) has been increasing in western societies during the last decades. Epidemiological studies to the public health impact of obesity are therefore warranted.
Visscher, T.L.S.
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Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

Arthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Long-Term Changes in Weight in Patients With Severe and Complicated Obesity After Completion of a Milk-Based Meal Replacement Programme

Frontiers in Nutrition, 2020
Introduction: Even with very significant short term weight loss with intensive dietary restriction, subsequent weight regain remains a challenge for most patients.
Razk Abdalgwad, Razk Abdalgwad, Razk Abdalgwad, Mohammed F. Rafey, Mohammed F. Rafey, Mohammed F. Rafey, Siobhan Foy, Siobhan Foy, Siobhan Foy, Micheál Newell, Micheál Newell, Micheál Newell, Colin Davenport, Colin Davenport, Colin Davenport, Derek T. O'Keeffe, Derek T. O'Keeffe, Derek T. O'Keeffe, Francis M. Finucane, Francis M. Finucane, Francis M. Finucane   +20 more
doaj   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J. S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source

2005-06 winter severe weather awareness

, 2005
Title from cover of PDF document (viewed Feb.
Ohio Committee for Severe Weather Awareness
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