Results 71 to 80 of about 652,669 (294)

Nomogram for pneumonia prediction among children and young people with cerebral palsy: A population-based cohort study.

PLoS ONE, 2020
BACKGROUND:Pneumonia is the leading cause of death among children and young people (CYP) with severe cerebral palsy (CP). Only a few studies used nomogram for assessing risk factors and the probability of pneumonia.
Tsu Jen Kuo, Chiao-Lin Hsu, Pei-Hsun Liao, Shih-Ju Huang, Yao-Min Hung, Chun-Hao Yin   +5 more
doaj   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Continuous Professional Oral Health Care Intervention Improves Severe Aspiration Pneumonia

Case Reports in Dentistry, 2019
Professional oral health care (POHC) is known to prevent aspiration pneumonia in patients with dysphagia and/or those at the perioperative stage of surgery. However, the effect of POHC on patients suffering from aspiration pneumonia remains unknown. Here,
Wakako Nawata, Yojiro Umezaki, Masahiro Yamaguchi, Masato Nakajima, Michiko Makino, Masahiro Yoneda, Takao Hirofuji, Takafumi Yamano, Hiroaki Ooboshi, Hiromitsu Morita   +9 more
doaj   +1 more source

Recommendations for diagnosing and treating severe Mycoplasma pneumoniae pneumonia in children: clinical practice protocols from the Third Affiliated Hospital of Sun Yat-sen University [PDF]

Xin yixue
Mycoplasma pneumoniae pneumonia （MPP） is a common cause of community-acquired pneumonia in children aged 5 and older in China. Although most affected children have favorable clinical prognosis， some cases can escalate into severe MPP due to risk factors ...
YANG Kexin, PAN Li, ZENG Jinqing, LI Zhongke, LI Xufeng, ZHU Lingping, LIANG Ying, YANG Lifen, ZHANG Kun, DAI Min, CHEN Zhuanggui, LI Yating
doaj   +1 more source

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease. [PDF]

, 2014
BACKGROUND: Inhaled corticosteroids (ICS) are anti-inflammatory drugs that have proven benefits for people with worsening symptoms of chronic obstructive pulmonary disease (COPD) and repeated exacerbations.
Agarwal, Allegra, Anderson, Anzueto, Bale, Blais, Bleecker, Bourbeau, Bourbeau, Briggs, Briggs, Briggs, British Thoracic Society, Burge, Burge, Burge, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Cates, Celli, Celli, Celli, Celli, Celli, Celli, Chavannes, Choudhury, Choudhury, Cipriani, Corhay, D'Urzo, Dahl, Dal Negro, Dalal, DiSantostefano, Dransfield, Drummond, Effing, Egede, Ernst, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Gizycki, Glenny, Grunsven, Grunsven, Halpin, Hanania, Hanania, Hanania, Hattotuwa, Horstman, Hunjan, Hunjan, Jarad, Jebrak, Jenkins, Jenkins, Johnell, Johnson, Jones, Jones, Jones, Jones, Jones, Jones, Kardos, Kardos, Keene, Korsgaard, Lacasse, Lange, Lapperre, Laptseva, Lofdahl, Lofdahl, Lofdahl, Lofdahl, Lofdahl, Lung Health Study Research Group, Mahler, Mahler, Marchand, Martinez, McDonough, McGarvey, Meer, Milanowski, Mirici, Monninkhof, Nannini, Nannini, Nitschmann, Ozol, Paggiaro, Partridge, Pauwels, Pauwels, Pauwels, Puhan, Renkema, Rennard, Roberts, Rossios, Sacchetta, Schermer, Senderovitz, Shaker, Shaker, Sharafkhaneh, Sharafkhaneh, Sin, Singanayagam, Singh, Song, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Suissa, Szafranski, Tashkin, Valk, Valk, Verhoeven, Verhoeven, Verhoeven, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Weir, Wouters, Wouters, Yang, Yildiz   +163 more
core   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Abnormal expression and clinical value analysis of long noncoding RNA cancer susceptibility candidate 2 in children with severe pneumonia complicated with respiratory failure

The Clinical Respiratory Journal, 2022
Objective Severe pneumonia occurs commonly in children and is the main cause of clinical infant mortality. This study tested the expression pattern of long noncoding RNA cancer susceptibility candidate 2 (CASC2) in the serum of children with severe ...
Jie Ni, Junfei Lu, Ding Lu
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Serum 25-hydroxyvitamin D levels in hospitalized adults with community-acquired pneumonia [PDF]

, 2018
Introduction: Community‐acquired pneumonia (CAP) is the infectious disease with the highest number of deaths worldwide. Several studies have shown an association between vitamin D deficiency and increases susceptibility to respiratory tract infections ...
Bool, British Thoracic Society Research Committee and the Public Health Laboratory Service, Charlson, Cukic, Fine, Gombart, Haan, Huang, Jolliffe, Kamen, Karonova, Kim, Kochanek, Lim, Liu, Lu, Luna, Mandell, Niederman, Pletz, Remmelts, Ross, Røysted, Schnoor, Schöttker, Toubi, Welte, Youssef   +27 more
core   +1 more source