Results 1 to 10 of about 3,153,921 (233)

Cortical Iron Reflects Severity of Alzheimer’s Disease

Journal of Alzheimer's Disease, 2017
Abnormal iron distribution in the isocortex is increasingly recognized as an in vivo marker for Alzheimer’s disease (AD). However, the contribution of iron accumulation to the AD pathology is still poorly understood.
Sara van Duijn, Marjolein Bulk, S. V. van Duinen, R. Nabuurs, M. van Buchem, L. van der Weerd, R. Natté   +6 more
semanticscholar   +5 more sources

Decreased severity of disease during the first global omicron variant covid-19 outbreak in a large hospital in tshwane, south africa

International Journal of Infectious Diseases, 2021
INTRODUCTION The coronavirus disease 2019 (COVID-19) first reported in Wuhan, China in December 2019 is a global pandemic that is threatening the health and wellbeing of people worldwide. To date there have been more than 274 million reported cases and 5.
F. Abdullah, J. Myers, D. Basu, G. Tintinger, V. Ueckermann, M. Mathebula, R. Ramlall, S. Spoor, T. De Villiers, Z. V. D. van der Walt, J. Cloete, P. Soma-Pillay, P. Rheeder, F. Paruk, A. Engelbrecht, V. Lalloo, M. Myburg, J. Kistan, W. von Hougenhouck-Tulleken, M. Boswell, G. Gray, R. Welch, L. Blumberg, W. Jassat   +23 more
semanticscholar   +1 more source

Evaluation of Interleukin-6 and its Association with the Severity of Disease in COVID-19 Patients

Indian Journal of Medical Specialities, 2020
Background: The present study was undertaken to determine the levels of interleukin-6 (IL-6) and evaluate its association with clinical presentation, severity, radiological imaging, management, and outcome in coronavirus disease (COVID-19) infection ...
Sudhir Bhandari, Govind Rankawat, Ajeet Singh, Dileep Wadhwani, Bhoopendra Patel   +4 more
doaj   +1 more source

PNPLA3 and TLL-1 Polymorphisms as Potential Predictors of Disease Severity in Patients With COVID-19

Frontiers in Cell and Developmental Biology, 2021
Albeit the pathogenesis of COVID-19 remains unclear, host’s genetic polymorphisms in genes involved in infection and reinfection, inflammation, or immune stimulation could play a role in determining the course and outcome.
Stefania Grimaudo, Emanuele Amodio, Rosaria Maria Pipitone, Carmelo Massimo Maida, Stefano Pizzo, Tullio Prestileo, Fabio Tramuto, Davide Sardina, Francesco Vitale, Alessandra Casuccio, Antonio Craxì   +10 more
doaj   +1 more source

Estimates of the severity of coronavirus disease 2019: a model-based analysis

medRxiv, 2020
Background: A range of case fatality ratio (CFR) estimates for COVID 19 have been produced that differ substantially in magnitude. Methods: We used individual-case data from mainland China and cases detected outside mainland China to estimate the time ...
R. Verity, L. Okell, I. Dorigatti, P. Winskill, C. Whittaker, N. Imai, G. Cuomo-Dannenburg, H. Thompson, P. Walker, H. Fu, A. Dighe, J. Griffin, M. Baguelin, S. Bhatia, A. Boonyasiri, A. Cori, Z. Cucunubá, R. FitzJohn, K. Gaythorpe, W. Green, A. Hamlet, W. Hinsley, D. Laydon, G. Nedjati-Gilani, S. Riley, S. V. van Elsland, E. Volz, Haowei Wang, Yuanrong Wang, X. Xi, C. Donnelly, A. Ghani, N. Ferguson   +32 more
semanticscholar   +1 more source

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

medRxiv, 2021
Treatment of severe COVID-19 is currently limited by clinical heterogeneity and incomplete understanding of potentially druggable immune mediators of disease.
David J. Zhichao Mark Chris Alice Brian M. Azim Carolina Ahern Ai Ainsworth Allan Allcock Angus Ansari Aran, D. Ahern, Zhichao Ai, M. Ainsworth, C. Allan, A. Allcock, B. Angus, M. Ansari, C. Arancibia-Cárcamo, D. Aschenbrenner, M. Attar, J. Baillie, E. Barnes, Rachael Bashford-Rogers, A. Bashyal, S. Beer, G. Berridge, Amy Beveridge, S. Bibi, T. Bicanic, L. Blackwell, P. Bowness, A. Brent, Andrew Brown, J. Broxholme, D. Buck, K. Burnham, H. Byrne, Susana Camara, Ivan Candido Ferreira, P. Charles, Wentao Chen, Yi-Ling Chen, A. Chong, E. Clutterbuck, M. Coles, C. Conlon, R. Cornall, Adam P. Cribbs, Fabiola Curion, E. Davenport, N. Davidson, S. Davis, C. Dendrou, J. Dequaire, Lea Dib, J. Docker, C. Dold, T. Dong, D. Downes, H. Drakesmith, S. Dunachie, David A. Duncan, Chris Eijsbouts, R. Esnouf, Alexis Espinosa, R. Etherington, Benjamin Fairfax, R. Fairhead, Hai Fang, S. Fassih, S. Felle, Maria Fernandez Mendoza, R. Ferreira, R. Fischer, T. Foord, Aden Forrow, J. Frater, A. Fries, Veronica Gallardo Sanchez, Lucy C. Garner, Clementine Geeves, Dominique Georgiou, L. Godfrey, T. Golubchik, M. Gomez Vazquez, A. Green, H. Harper, H. Harrington, R. Heilig, Svenja S. Hester, J. Hill, Charles J Hinds, C. Hird, L. Ho, Renee S. Hoekzema, Benjamin Hollis, J. Hughes, P. Hutton, Matthew Jackson-Wood, Ashwin Jainarayanan, Anna James-Bott, Kathrin Jansen, K. Jeffery, E. Jones, L. Jostins, G. Kerr, David Kim, P. Klenerman, J. Knight, Vinod Kumar, Piyush Kumar Sharma, P. Kurupati, A. Kwok, Angela Lee, Aline Linder, T. Lockett, L. Lonie, M. Lopopolo, Martyna Lukoseviciute, Jian Luo, S. Marinou, B. Marsden, J. Martinez, P. Matthews, M. Mazurczyk, S. McGowan, S. McKechnie, A. Mead, A. Mentzer, Yuxin Mi, C. Monaco, Ruddy Montadon, G. Napolitani, I. Nassiri, A. Novak, Darragh P. O’Brien, D. O’Connor, D. O’Donnell, G. Ogg, L. Overend, I. Park, I. Pavord, Yanchun Peng, F. Penkava, Mariana Pereira Pinho, Elena Pérez, A. Pollard, F. Powrie, B. Psaila, T. Quan, E. Repapi, S. Revale, L. Silva-Reyes, Jean-Baptiste Richard, C. Rich-Griffin, Thomas G. Ritter, C. Rollier, M. Rowland, Fabian Ruehle, M. Salio, S. Sansom, Raphael Sanches Peres, Alberto Santos Delgado, T. Sauka-Spengler, R. Schwessinger, G. Scozzafava, G. Screaton, A. Seigal, M. Semple, M. Sergeant, Christina Simoglou Karali, David Sims, D. Skelly, H. Slawinski, Alberto Sobrinodiaz, N. Sousos, Lizzie Stafford, L. Stockdale, M. Strickland, Otto Sumray, Bo Sun, Chelsea A. Taylor, Stephen S. Taylor, A. Taylor, S. Thongjuea, H. Thraves, J. Todd, A. Tomic, Orion Tong, A. Trebes, D. Trzupek, F. A. Tucci, L. Turtle, I. Udalova, H. Uhlig, Erinke van Grinsven, I. Vendrell, M. Verheul, Alexandru-Ioan Voda, Guanlin Wang, Lihui Wang, Dapeng Wang, P. Watkinson, R. Watson, Michael Weinberger, J. Whalley, L. Witty, Katherine Wray, Luzheng Xue, H. Yeung, Z. Yin, Rebecca K. Young, J. Youngs, Ping Zhang, Y. Zurke   +205 more
semanticscholar   +1 more source

Non-motor symptoms in patients with Parkinson’s disease in Babol, North of Iran [PDF]

Romanian Journal of Neurology, 2019
Introduction. Non-motor symptoms (NMS) are common in Parkinson’s disease. It can be predominant as the disease advances, thereby constituting a major source of disease burden for patients.
Seyed Mohammad Masood Hojjati, Arman Farrasat, Hoda Naghshineh, Ali Alizadeh-Khatir, Alijan Ahmadi Ahangar, Payam Saadat, Shayan Alijanpour   +6 more
doaj   +1 more source

Measurement of disease severity in cutaneous autoimmune diseases [PDF]

F1000Prime Reports, 2013
The development of disease-specific outcome instruments for several autoimmune skin diseases including cutaneous lupus erythematosus (CLE), dermatomyositis, vitiligo, pemphigus and alopecia areata has facilitated the objective assessment of disease in clinical trials.
Anyanwu, Cynthia, Langenhan, Jamie, Werth, Victoria P.   +2 more
openaire   +2 more sources

Assessing Severity of Disease in Patients with Ulcerative Colitis

Gastroenterology Clinics of North America, 2020
Ulcerative colitis (UC) is a chronic disease that can present at various stages of disease activity and severity. Traditionally, severity scoring has focused on disease activity during a single moment with various tools, including patient-reported ...
B. Pabla, D. Schwartz
semanticscholar   +1 more source

Radiographic study of Sever's disease

Experimental and Therapeutic Medicine, 2020
X-ray and MRI differences of calcaneal epiphysis between Sever's disease patients and normal children were compared and analyzed to raise awareness of Sever's disease. A total of 98 children with Sever's disease were enrolled in the study, including 72 males and 26 females. Among them, 6 patients underwent MRI.
Gao, Yan, Liu, Jia, Li, Yifang, Liu, Qing, Xu, Shuhua   +4 more
openaire   +3 more sources