Results 91 to 100 of about 177,712,728 (307)

Severity-stratified diagnostic markers in relation to symptom and total disease days.

open access: yes
Four diagnostic markers (systolic blood pressure, pulse, haemoglobin (Hb) and haematocrit (HCT)) show different correlations with pre-hospitalisation symptom days with little difference between disease severity scores 1 and 2.
Wim A. Fleischmann (17873822)   +13 more
core   +2 more sources

Associations between serum complement component 3a and sC5b⁃9 levels with the prognosis of sepsis patients

open access: yesZhongguo linchuang yanjiu
"Objective To investigate the associations of serum complement component 3a(C3a)and soluble terminalcomplement complex C5b⁃9(sC5b⁃9)levels with the severity of sepsis and 28⁃day clinical prognosis among patients,and to provide new biomarker references ...
SU Yixing,BAO Lei,YU Jun'an,GU Zhijian
doaj   +1 more source

Effect of Disease Severity on the Quality of Life and Sense of Stigmatization in Psoriatics

open access: yesClinical, Cosmetic and Investigational Dermatology, 2021
Beata Kowalewska,1 Barbara Jankowiak,1 Mateusz Cybulski,1 Elżbieta Krajewska-Kułak,1 Dzmitry Fiodaravich Khvorik2 1Department of Integrated Medical Care, Medical University of Bialystok, Bialystok, Poland; 2Department of Dermatovenerology, Medical ...
Kowalewska B   +4 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

COPD exacerbations by disease severity in England

open access: yes, 2016
Evie Merinopoulou,1 Mireia Raluy-Callado,1 Sreeram Ramagopalan,1 Sharon MacLachlan,1 Javaria Mona Khalid2 1Real-World Evidence, Evidera, 2Takeda Development Centre Europe Ltd, London, UK Objectives: Exacerbations of chronic obstructive pulmonary ...
MacLachlan S   +4 more
core  

Severity of airflow obstruction in Chronic Obstructive Pulmonary Disease (COPD): proposal for a new classification [PDF]

open access: yes, 2017
Current classifications of Chronic Obstructive Pulmonary Disease (COPD) severity are complex and do not grade levels of obstruction. Obstruction is a simpler construct and independent of ethnicity.
Coton, Sonia,   +52 more
core   +1 more source

Feasibility study on application of different disease severity scoring systems in classifying nursing grading of patients in ICU

open access: yesHuli yanjiu, 2020
ObjectiveTo explore the feasibility of using APACHE Ⅱ,SAPS2,MPM Ⅱ three commonly used disease severity scoring systems to classify the nursing grading of ICU patients.MethodsA cross-sectional study was conducted on 300 ICU patients in a tertiary hospital.
SHI Qingqing   +5 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A comparison of raters and disease assessment methods for estimating disease severity for purposes of hypothesis testing

open access: yes, 2014
Assessment of disease severity is most often made visually, and estimates can be inaccurate. Nearest percent estimates (NPEs) of Septoria leaf blotch on leaves of winter wheat by four raters (R1-R4) assessing non-treated (NT) and fungicide-treated (FT ...
Delfosse, Philippe   +5 more
core  

Fluctuations in number of Cercospora beticola conidia in relationship to environment and disease severity in sugar beet [PDF]

open access: yes, 2009
Cercospora leaf spot, caused by Cercospora beticola, is the most damaging foliar disease of sugar beet in Minnesota (MN) and North Dakota (ND). Research was conducted to characterize the temporal progression of aerial concentration of C. beticola conidia
Qi, Aiming   +6 more
core   +1 more source

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