Results 101 to 110 of about 177,712,728 (307)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Illness perceptions and stress: mediators between disease severity and psychological well-being and quality of life among patients with Crohn’s disease

, 2016
Maochen Zhang,1,* Liwen Hong,1,* Tianyu Zhang,1 Yun Lin,1 Sichang Zheng,1 Xiaolin Zhou,1 Rong Fan,1 Zhengting Wang,1 Chenli Zhang,2 Jie Zhong1 1Department of Gastroenterology, 2Exclusive Medical Center, Ruijin Hospital, School of Medicine, Shanghai Jiao
Hong L, Zhang T, Zheng S, Zhang M, Lin Y, Zhang C, Zhong J, Zhou X, Fan R, Wang Z   +9 more
core  

Relationship between serum Midkine and Omentin-1 levels and the severity of sepsis in patients and their prognostic value

Libyan Journal of Medicine
To explore the relationship between serum levels of midkine and omentin-1 and the severity of sepsis in patients, and their prognostic value. A retrospective analysis was conducted on the clinical data of 180 sepsis patients. According to the severity of
Lin Gao, Qindi Liu, Zhiming Kuang, Shanbin Yuan   +3 more
doaj   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Serum homocysteine is associated with the severity of primary chronic venous disease

, 2016
Objective: This study was conducted to assess whether serum homocysteine concentration was associated with the severity of primary chronic venous disease. Design: Cross-sectional study.
Tosenovsky, Patrik, Velu, Ramesh, Smith, Ross K, Quigley, Frank, Golledge, Jonathan, Smith, Ross, Bradshaw, Barbara, Buettner, Petra   +7 more
core   +1 more source

The Possible Bidirectional Relationship between Disease Severity in Androgenetic Alopecia and Seborrheic Dermatitis: A Cross-Sectional Study in a Tertiary Care Hospital

Indian Dermatology Online Journal
Background: Seborrheic dermatitis (SD) is the most common concurrent disease in patients with androgenetic alopecia (AGA). There are inadequate data to determine whether there is a relationship between AGA severity and SD severity.
Dilek Menteşoğlu, Gökçe Işıl Kurmuş, Selda Pelin Kartal   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

correlation between serum Vitamin D3 Level and Disease Severity in the Patients with Chronic Obstructive Pulmonary Disease (COPD) [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان
Background and Aim: Chronic obstructive pulmonary disease (COPD) which is characterized by symptoms such as dyspnea and cough is the fourth leading cause of death worldwide.
sahar rezaei nejad, hamid bakhshi aliabad, hosein basirat, haniye maleki, fatemeh amin, mahdi karimi   +5 more
doaj  

Identifying Risk Factors for Impaired Pulmonary Function in COVID-19 Patients: Cross-Sectional Study

Central Asian Journal of Medical Sciences
Objective: COVID-19 has an impact on various organs, including heart, kidney, lung, and liver. However, respiratory system has been the primary organ mostly affected, ranging from asymp tomatic to critical stages of the disease.
Odonchimeg Bayaraa, Allabyergyen Myeryemkhaan, Gaamaa Jamsran, Norjmaa Boldbaatar, Sarantuya Jav, Mukhbayarlakh Sonomjamts, Ichinnorov Dashtseren   +6 more
doaj   +1 more source