Results 141 to 150 of about 3,182,382 (382)

Modelling of lung cancer survival data for critical illness insurances [PDF]

open access: yesarXiv, 2016
We derive a general multiple state model for critical illness insurances. In contrast to the classical model, we take into account that the probability of death for a dread disease sufferer may depend on the duration of the disease, and the payment of benefits associated with a severe disease depends not only on the diagnosis but also on the disease ...
arxiv  

In Vivo‐Like Scaffold‐Free 3D In Vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi   +1 more
wiley   +1 more source

An analysis and solution of ill-conditioning in physics-informed neural networks [PDF]

open access: yesarXiv
Physics-informed neural networks (PINNs) have recently emerged as a novel and popular approach for solving forward and inverse problems involving partial differential equations (PDEs). However, achieving stable training and obtaining correct results remain a challenge in many cases, often attributed to the ill-conditioning of PINNs.
arxiv  

Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold   +2 more
wiley   +1 more source

On Regularizing Effects of MINRES and MR-II for Large-Scale Symmetric Discrete Ill-Posed Problems [PDF]

open access: yesJournal of Computational and Applied Mathematics, 320 (2017): 145-163, 2015
For large scale symmetric discrete ill-posed problems, MINRES and MR-II are often used iterative regularization solvers. We call a regularized solution best possible if it is at least as accurate as the best regularized solution obtained by the truncated singular value decomposition (TSVD) method.
arxiv  

The Imbalance between Coagulation and Fibrinolysis is Related to the Severity of the Illness and the Prognosis in Sepsis [PDF]

open access: gold, 1999
Kwang Joo Park   +7 more
openalex   +1 more source

Advancing Metal–Organic Framework‐Based Composites for Effective Chemical Warfare Agent Detoxification under Real‐World Conditions

open access: yesAdvanced Materials, EarlyView.
This review describes recent developments in the design and synthesis of metal–organic frameworks (MOF)/textile composites for the detoxification of chemical warfare agent and simulants with extensive discussion on the advantages and disadvantages of different methods.
Zhihua Cheng   +4 more
wiley   +1 more source

Predicting maternal healthcare seeking behaviour in Afghanistan: exploring sociodemographic factors and women's knowledge of severity of illness. [PDF]

open access: yesBMC Pregnancy Childbirth, 2023
Tawfiq E   +7 more
europepmc   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

open access: yesAdvanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak   +2 more
wiley   +1 more source

Patterns of community violence exposure among urban adolescents and their associations with adjustment

open access: yesAmerican Journal of Community Psychology, Volume 70, Issue 3-4, Page 265-277, December 2022., 2022
Abstract Community violence exposure is prevalent among urban and marginalized adolescents. Although there is strong evidence that community violence exposure is associated with negative consequences, prior studies and theories suggest that these associations may differ as a function of specific characteristics of exposure.
Sarah K. Pittman, Albert D. Farrell
wiley   +1 more source

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