Results 51 to 60 of about 957,939 (375)

Association of Initial Illness Severity and Outcomes After Cardiac Arrest With Targeted Temperature Management at 36 °C or 33 °C

JAMA Network Open, 2020
Key Points Question What is the optimal target temperature for targeted temperature management (TTM) in comatose patients after cardiac arrest? Findings In a cohort study of 1319 patients, of whom 911 did not have severe cerebral edema or highly ...
C. Callaway, Patrick J Coppler, John W Faro, Jacob S. Puyana, P. Solanki, C. Dezfulian, A. Doshi, J. Elmer, A. Frisch, F. Guyette, M. Okubo, J. Rittenberger, A. Weissman   +12 more
semanticscholar   +1 more source

SNAPPE II: ANALYSIS OF ACCURACY AND DETERMINATION OF THE CUTOFF POINT AS A DEATH PREDICTOR IN A BRAZILIAN NEONATAL INTENSIVE CARE UNIT

Revista Paulista de Pediatria, 2020
Objective: To analyze the accuracy of the Score for Neonatal Acute Physiology Perinatal Extension (SNAPPE II) as a death predictor, to determine the cutoff point for mortality, and to analyze the association of independent variables with death. Methods:
Maria Marcia Farias Trajano Fontenele, Cristiana Ferreira Silva, Álvaro Jorge Madeiro Leite, Eveline Campos Monteiro Castro, Francisco Herlânio Costa Carvalho, Ana Valeska Siebra e Silva   +5 more
doaj   +2 more sources

Pressure injury in Australian public hospitals: a cost-of-illness study [PDF]

, 2015
Objective: Pressure injuries (PI) are largely preventable and can be viewed as an adverse outcome of a healthcare admission, yet they affect millions of people and consume billions of dollars in healthcare spending.
Allman, Antonio, Asimus, Asimus, Banks, Bennett, Brem, Brito, Dealey, Franks, Gallagher, Gorecki, Graves, Graves, Graves, Graves, Gunningberg, Gunningberg, House, Jackson, Kottner, Legood, Lyder, McNair, Nelson, Padula, Pham, Prentice, Russo, Severens, Shahin, Shemilt, Vanderwee, Vanderwee, Vanderwee   +34 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Cluster-randomized trial of the implementation of the Responses to Illness Severity Quantification (RISQ) system in children with acute malnutrition 6 to 59 months of age in Ngouri, Chad: the CRIMSON trial protocol

Trials
Background The Responses to Illness Severity Quantification (RISQ) System is a scientifically developed clinical decision support tool comprised of four parts: (1) a validated 7-item severity of illness score, (2) age-specific documentation forms, (3 ...
Nancy M. Dale, Youssouf Djidita Hagre, Susan Shepherd, George Tomlinson, Stanley Zlotkin, Masra Ngaradoum, Mahmat Bechir, Marius Madjissem, Charles Tehoua, Christopher Parshuram   +9 more
doaj   +1 more source

Emotional dysfunction in schizophrenia spectrum psychosis: the role of illness perceptions [PDF]

, 2006
Background. Assessing illness perceptions has been useful in a range of medical disorders. This study of people with a recent relapse of their psychosis examines the relationship between illness perception, their emotional responses and their attitudes ...
Bebbington, PE, Dunn, G, Fowler, D, Freeman, D, Garety, PA, Kuipers, E, Watson, PWB, Weinman, J   +7 more
core  

Lifetime Bipolar Disorder comorbidity and related clinical characteristics in patients with primary Obsessive Compulsive Disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) [PDF]

, 2019
IntroductionBipolar disorder (BD) and obsessive compulsive disorder (OCD) are prevalent, comorbid, and disabling conditions, often characterized by early onset and chronic course.
Benatti, Beatrice, Cirnigliaro, Giovanna, Dell'Osso, Bernado, Fineberg, Naomi, Grancini, Benedetta, Grassi, Giacomo, Hollander, Eric, Hranov, Georgi, Hranov, Luchezar, Karamustafalioglu, Oguz, Lanzagorta, Nuria, Lochner, Christine, Marazziti, Donatella, Menchon, Josè M, Nicolini, Humberto, Pallanti, Stefano, Rodriguez, Carolyn I, Stein, Dan J., Van Ameringen, Michael, Vismara, Matteo, Zohar, Joseph   +20 more
core   +4 more sources

Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study

British medical journal, 2020
Objective To describe outcomes of people admitted to hospital with coronavirus disease 2019 (covid-19) in the United States, and the clinical and laboratory characteristics associated with severity of illness. Design Prospective cohort study.
C. Petrilli, Simon A. Jones, Jie Yang, Harish Rajagopalan, Luke O’Donnell, Yelena Chernyak, Katie A. Tobin, R. Cerfolio, F. François, Leora I. Horwitz   +9 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source