Results 51 to 60 of about 937,579 (305)
Background: On March 11, 2020, the World Health Organization (WHO) confirmed COVID-19 as a pandemic. COVID-19 has infected more than 5.5 million people worldwide, resulting in more than 3,47,000 fatalities.
Mamta Kishor Shewte +4 more
doaj +1 more source
Severity of Illness Scores May Misclassify Critically Ill Obese Patients*
Objective: Severity of illness scores rest on the assumption that patients have normal physiologic values at baseline and that patients with similar severity of illness scores have the same degree of deviation from their usual state.
Rodrigo Deliberato +8 more
openaire +4 more sources
Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright +13 more
wiley +1 more source
The Association of Zinc Serum Level with Age, Sex and Disease Severity in Acne Vulgaris Patients
Background: Acne vulgaris is a chronic inflammatory disease of pilosebaceous follicles. It is one of the most important skin disorders during adolescence. Zinc is one of essential trace elements in the body that has major roles in maintaining health. The
Gholam Hossein Ghafarpour +2 more
doaj
Predictors of employment in bipolar disorder : a systematic review [PDF]
Background Severe work impairment can be present for a considerable proportion of the course of bipolar disorder (BD) and is costly for governments, services and individuals.
Bonnín +47 more
core +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Pressure injury in Australian public hospitals: a cost-of-illness study [PDF]
Objective: Pressure injuries (PI) are largely preventable and can be viewed as an adverse outcome of a healthcare admission, yet they affect millions of people and consume billions of dollars in healthcare spending.
Allman +34 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
ImportanceMortality prediction among critically ill patients in resource limited settings is difficult. Identifying the best mortality prediction tool is important for counseling patients and families, benchmarking quality improvement efforts, and ...
B. Jason Brotherton +11 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

