Background We sought to determine the mediating effects of magnetic resonance imaging (MRI) biomarkers at term gestation on the relationship between perinatal illness severity and neurodevelopment.
J. Logan+7 more
semanticscholar +1 more source
How are normal sleeping controls selected? A systematic review of cross-sectional insomnia studies, and a standardised method to select healthy controls for sleep research [PDF]
There appears to be some inconsistency in how normal sleepers (controls) are selected and screened for participation in research studies for comparison with insomnia patients.
Louise Beattie+59 more
core +5 more sources
Charlson Comorbidity Index and other predictors of in-hospital mortality among adults with community-acquired pneumonia [PDF]
Objective: To compare the performance of Charlson Comorbidity Index (CCI) with those of the mental Confusion, Urea, Respiratory rate, Blood pressure, and age = 65 years (CURB-65) score and the Pneumonia Severity Index (PSI) as predictors of all-cause in ...
Laura Fuchs Bahlis+2 more
doaj +4 more sources
Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease? [PDF]
BackgroundAnorexia nervosa carries the highest mortality rate of any psychiatric disorder. Even the most critically ill anorexic patients may present with normal 'standard' laboratory values, underscoring the need for a new sensitive biomarker.
Flierl, Michael A+5 more
core +2 more sources
Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome [PDF]
Background: Sepsis is one of the leading causes of death in the UK. Aims: The aims of this study were to identify the rate of inactive antimicrobial therapy (AMT) in the ICU and whether inactive AMT had an effect on in hospital mortality, ICU ...
Booth, M.G.+4 more
core +1 more source
Alteraciones bioquímicas como marcadores predictores de gravedad en pacientes con fiebre por dengue
Introducción. El dengue es la infección transmitida por mosquitos más importante en el mundo. Existe información de que las alteraciones bioquímicas pueden utilizarse como herramientas predictoras de gravedad del dengue. Objetivo.
Luis Ángel Villar-Centeno+3 more
doaj +1 more source
Parkinsonian motor impairment predicts personality domains related to genetic risk and treatment outcomes in schizophrenia [PDF]
Identifying endophenotypes of schizophrenia is of critical importance and has profound implications on clinical practice. Here we propose an innovative approach to clarify the mechanims through which temperament and character deviance relates to risk for
Alemán, Gabriela González+15 more
core +2 more sources
The small bowel is affected in the vast majority of patients with Crohn's Disease (CD). Small bowel capsule endoscopy (SBCE) has a very high sensitivity for the detection of CD-related pathology, including early mucosal lesions and/or those located in ...
Bruno Rosa+5 more
doaj +1 more source
Weight Loss and Illness Severity in Adolescents With Atypical Anorexia Nervosa. [PDF]
BACKGROUND:Lower weight has historically been equated with more severe illness in anorexia nervosa (AN). Reliance on admission weight to guide clinical concern is challenged by the rise in patients with atypical anorexia nervosa (AAN) requiring ...
Accurso, Erin C+13 more
core
Bright light therapy as part of a multicomponent management program improves sleep and functional outcomes in delirious older hospitalized adults. [PDF]
ObjectiveDelirium is associated with poor outcomes following acute hospitalization. A specialized delirium management unit, the Geriatric Monitoring Unit (GMU), was established.
Ancoli-Israel, Sonia+4 more
core +1 more source