The development of a new measure of quality of life for children with congenital cardiac disease [PDF]
, 2006 The purpose of the study was to develop a questionnaire measuring health-related R1 quality of life for children and adolescents with congenital heart disease, the ConQol, that would have both clinical and research applications.
Birks, Y +8 more
core +1 more source
Delta neutrophil index as an early marker of disease severity in critically ill patients with sepsis [PDF]
BMC Infectious Diseases, 2011 Abstract Background The immature granulocyte count has been reported to be a marker of infection and sepsis. The difference in leukocyte subfractions (delta neutrophil index, DNI) in ADVIA 2120 reflects the fraction of circulating immature granulocytes in the blood.
Kim Se +10 more
openaire +4 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Psychological symptoms in obesity and related factors [PDF]
, 2015 Introduction: This study aimed to investigate the relationship between levels of depression and anxiety symptoms and quality of life, self-esteem in obesity.
Değirmenci, T. +4 more
core +1 more source
Tissue Doppler Septal Tei Index Indicates Severity of Illness in Pediatric Patients With Congestive Heart Failure [PDF]
Pediatric Cardiology, 2013 The Doppler Tei index is an independent predictor of outcomes in adult heart failure. Tissue Doppler imaging (TDI) may be a superior method to measure the Tei index in children because it is less affected by heart rate variability. We hypothesized that the TDI Tei index reflects severity of illness in pediatric heart failure.
Aura A, Sanchez Mejia +8 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Orthodontic treatment need in a group of 9-12-year-old Brazilian schoolchildren
Brazilian Oral Research, 2009 The present study aimed to evaluate the need for orthodontic treatment in Brazilian schoolchildren presenting both late mixed dentition and early permanent dentition as well as to determine the possible factors associated with this necessity.
Patricia Fernanda Dias, Rogerio Gleiser
doaj +1 more source
Comparisons of APACHE II, CURB-65, Pneumonia severity index, and CHA2DS2-VAS score on new onset cardiovascular events, including atrial fibrillation, for critical illness with pneumonia [PDF]
, 2023 Tian Wang, Ya‐Lan Lin
openalex +1 more source
Incorporation of Biomarkers with the Renal Angina Index for Prediction of Severe AKI in Critically Ill Children [PDF]
Clinical Journal of the American Society of Nephrology, 2014 Novel AKI biomarkers carry variable performance for prediction of AKI in patients with heterogeneous illness. Until utility is demonstrated in critically ill patients outside of the cardiopulmonary bypass population, AKI biomarkers are unlikely to gain widespread implementation. Operationalization of an AKI risk stratification methodology, termed renal
Rajit K, Basu +5 more
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source