Results 111 to 120 of about 165 (164)

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

Transmission of Radio‐Frequency Waves and Nuclear Magnetic Resonance in Lanthanum Superhydrides

Advanced Science, EarlyView.
1H NMR and radio‐frequency transmission measurements of lanthanum superhydrides at 165 GPa reveals a transition at 260–280 K by a strong suppression of the signal intensity, significant changes in NMR spectra, including a dramatic decrease of the relaxation rate 1/T1T, and pronounced shielding effect, which may have a superconducting nature.
Dmitrii V. Semenok, Florian Bärtl, Di Zhou, Toni Helm, Sven Luther, Joachim Wosnitza, Ivan A. Troyan, Viktor V. Struzhkin, Hannes Kühne   +8 more
wiley   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Emerging Device Applications From Strong Light–Matter Interactions in 2D Materials

Advanced Science, EarlyView.
Two‐dimensional semiconductors enable extremely compact optoelectronic devices such as solar cells, sensors, LEDs, and lasers. Their strong light–matter interactions allow efficient light emission, detection, and energy conversion. This review article discusses the recent progress in integrating these materials with optical cavities and nanostructures ...
Janani Archana K, Kumar Shwetabh, Reyas Ali, Ramji Velayutham, Koustav Das, Abhishek Mondal, Prashant Kumar, Surendra B. Anantharaman   +7 more
wiley   +1 more source

BARRIER PROBABILITIES AND MAXIMUM SEVERITY OF RUIN FOR A RENEWAL RISK MODEL [PDF]

International Journal of Theoretical and Applied Finance, 2007
In this paper, we consider a renewal risk model with dividend barrier, in which the claim inter-occurrence times are generalized exponential. We obtain explicit expression for the probability of absorption by an upper barrier b, before ruin occurs when the claim amount distribution is either mixed exponential or Gamma. We apply these results to obtain
K. K. THAMPI, M. J. JACOB, N. RAJU
openaire   +1 more source

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Approximate solutions of severity of ruins

Blätter der DGVFM, 1996
Summary: Let \(G(u,y)\) be the severity of ruin, i.e. the probability that, starting with the initial surplus \(u\), ruin occurs and the deficit at the time of ruin is less than \(y\). The authors determine approximate solutions for the severity of ruin using a numerical algorithm based on cubic spline approximation.
Di Lorenzo, Emilia, Tessitore, Gerarda
openaire   +1 more source

On some aspects of Maximum Severity of Ruin

Metamorphosis: A Journal of Management Research, 2016
The authors of this article engage ruin theory as a mathematical basis for quantifying the financial risks in insurance industry. Considering a classical risk model with dividend barrier, it is calibrated to obtain the maximum probability of ruin when the claim amount distribution is either exponential or Erlangian.
Palash Ranjan Das, Tripti Chakrabarti
openaire   +1 more source

The severity of ruin in a discrete semi-Markov risk model

Stochastic Models, 2002
In this paper we introduce a discrete time semi-Markov risk model. We derive a recursive system for finding the probability of ruin and the distribution of the severity of ruin in a particular case...
Reinhard, Jean-Marie, Snoussi, Mohammed
openaire   +1 more source

Severity of ruin in a Markov-dependent risk model

Wuhan University Journal of Natural Sciences, 2009
We study the severity of ruin in a Markov-dependent risk model in which the claim interarrivals and claim amounts are influenced by an external Markov chain. A system of integro-differential equation of the severity of ruin, given the initial environment state, is derived. Explicit formulas for the severity of ruin are obtained when the initial surplus
Juan Liu, Jiancheng Xu, Yijun Hu
openaire   +1 more source

Explicit form of finite-time severity of ruin for phase-distributed claim sizes

Blätter der DGVFM, 1999
Summary: By applying results of reliability theory bounds on the net premium of the classical excess-of-loss cover are given.
El Bantli, Faouzi, Snoussi, Mohammed
openaire   +2 more sources