Results 61 to 70 of about 662,113 (303)

Long-term prediction of adherence to continuous positive air pressure therapy for the treatment of moderate/severe obstructive sleep apnea syndrome [PDF]

, 2018
BACKGROUND: Continuous positive airway pressure (CPAP) therapy is a highly effective treatment for obstructive sleep apnea syndrome (OSAS). However, poor adherence is a limiting factor, and a significant proportion of patients are unable to tolerate CPAP.
Angelico F, Baratta F, Brunori M, Bucci T, Del Ben M, Fabiani M, Fabiani V, Lillo R, Loffredo L, Pannitteri G, Pastori D   +10 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Prediction Models of Severity in Acute Biliary Pancreatitis

Diagnostics
Background: Acute pancreatitis is a common condition with a variable prognosis. While the overall mortality rate of acute pancreatitis is relatively low, ranging between 3 and 5% in most cases, severe forms can result in significantly higher morbidity ...
Iulia Ratiu, Renata Bende, Camelia Nica, Oana Budii, Calin Burciu, Andreea Barbulescu, Tudor Moga, Bogdan Miutescu, Roxana Sirli, Mirela Danila, Alina Popescu, Felix Bende   +11 more
doaj   +1 more source

Clinical selection strategies to identify ischemic stroke patients with large anterior vessel occlusion: results from SITS-ISTR (Safe Implementation of Thrombolysis in Stroke International Stroke Thrombolysis Registry) [PDF]

, 2017
Background and Purpose—The National Institutes of Health Stroke Scale (NIHSS) correlates with presence of large anterior vessel occlusion (LAVO). However, the application of the full NIHSS in the prehospital setting to select patients eligible for ...
Abdul-Rahim, Azmil H., Ahmed, Niaz, Audebert, Heinrich J., Broderick, Joseph P., Cooray, Charith, Endres, Matthias, Khatri, Pooja, Kleindorfer, Dawn, Lees, Kennedy R., MacIsaac, Rachael L., Nolte, Christian H., Scheitz, Jan F., Sucharew, Heidi, Wahlgren, Nils   +13 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A Hybrid K‐Means Clustering and Ensemble Model for Predicting Road Traffic Accident Severity

Engineering Reports
Road traffic accidents remain a critical global challenge, causing millions of deaths and economic losses. Understanding critical factors and accurately predicting accident severity are essential to mitigating these impacts.
Getachew Getu Enyew, Solomon Zemene Melese, Temesgen Tadesse Feisa, Mulugeta Linger Tariku   +3 more
doaj   +1 more source

SevPredict: Exploring the Potential of Large Language Models in Software Maintenance

AI
The prioritization of bug reports based on severity is a crucial aspect of bug triaging, enabling a focus on more critical issues. Traditional methods for assessing bug severity range from manual inspection to the application of machine and deep learning
Muhammad Ali Arshad, Adnan Riaz, Rubia Fatima, Affan Yasin   +3 more
doaj   +1 more source

Establishment and validation of early prediction model for hypertriglyceridemic severe acute pancreatitis

Lipids in Health and Disease, 2023
Background The prevalence of hypertriglyceridaemia-induced acute pancreatitis (HTG-AP) is increasing due to improvements in living standards and dietary changes. However, currently, there is no clinical multifactor scoring system specific to HTG-AP. This
Yi Shuanglian, Zeng Huiling, Lin Xunting, Deng Yifang, Lin Yufen, Xie Shanshan, Si Lijuan, Liu Yunpeng   +7 more
doaj   +1 more source

Relationship Between Sleep and Behavior in Autism Spectrum Disorder: Exploring the Impact of Sleep Variability. [PDF]

, 2020
Objective:The relationship between sleep (caregiver-reported and actigraphy-measured) and other caregiver-reported behaviors in children and adults with autism spectrum disorder (ASD) was examined, including the use of machine learning to identify sleep ...
Bangerter, Abigail, Boice, Matthew, Chatterjee, Meenakshi, Dawson, Geraldine, Esbensen, Anna, Goodwin, Matthew S, Hendren, Robert, Leventhal, Bennett, Lewin, David, Manyakov, Nikolay V, Ness, Seth, Pandina, Gahan, Shic, Frederick, Skalkin, Andrew   +13 more
core  

Parametric rolling in regular head waves of the Kriso container ship : numerical and experimental investigation in shallow water [PDF]

, 2019
The IMO Intact Stability Code considers the parametric rolling phenomenon as one of the stability failure modes because of the larger roll angles attained.
Delefortrie, Guillaume, Lataire, Evert, Tello Ruiz, Manasés, Vantorre, Marc, Villagomez, José   +4 more
core   +1 more source