Results 111 to 120 of about 82,704 (334)

Hyperglycemia as an atypical finding of malignant hyperthermia: A case report and literature review

open access: yesJournal of Diabetes Investigation, EarlyView.
A 13‐month‐old toddler presented with an atypical symptom – hyperglycemia – during a malignant hyperthermia crisis. During MH, hyperglycemia may result from intracellular calcium leakage in muscle cells, suggesting a potential association between MH susceptibility and hyperglycemia.
Huai‐Jhih Sun   +4 more
wiley   +1 more source

Sevoflurane postconditioning enhanced hippocampal neuron resistance to global cerebral ischemia induced by cardiac arrest in rats through PI3K/Akt survival pathway

open access: yesFrontiers in Cellular Neuroscience, 2016
The purpose of this current study is to evaluate whether improvement of mitochondrial dysfunction was involved in the therapeutic effect of sevoflurane postconditioning in global cerebral ischemia after cardiac arrest (CA) via the PI3K/Akt pathway.
Zhihua Wang   +5 more
doaj   +1 more source

Sevoflurane alleviates LPS-induced acute lung injury via the microRNA-27a-3p/TLR4/MyD88/NF-κB signaling pathway

open access: yesInternational Journal of Molecular Medicine, 2019
Acute lung injury (ALI) is a critical syndrome that is associated with a high morbidity and mortality in patients. Sevoflurane has a lung protective effect in ALI as it reportedly has anti-inflammatory and apoptotic-regulating activity.
Yunfei Wang   +5 more
semanticscholar   +1 more source

Stabilisation of thoracolumbar vertebral fractures and luxations in cats with a polyaxial screw/rod system

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives The purpose of this study was to determine clinical and neurological data on the stabilisation of thoracolumbar region fractures or luxations in cats with the polyaxial screw rod system. Materials and Methods The study included 16 cats with thoracic and/or lumbar fractures, luxations and/or instability.
M. N. Çetin, Y. S. Şirin
wiley   +1 more source

Gut Microbiota–Metabolite–Brain Axis Reconstitution Reverses Sevoflurane-Induced Social and Synaptic Deficits in Neonatal Mice

open access: yesResearch
Background: The mechanisms underlying social dysfunction caused by repeated sevoflurane in early life remain unclear. Whether the gut microbiota–metabolite–brain axis is involved in the mechanism of sevoflurane developmental neurotoxicity still lacks ...
Youyi Zhao   +12 more
doaj   +1 more source

Sugammadex-Enhanced Neuronal Apoptosis following Neonatal Sevoflurane Exposure in Mice

open access: yesAnesthesiology Research and Practice, 2016
In rodents, neonatal sevoflurane exposure induces neonatal apoptosis in the brain and results in learning deficits. Sugammadex is a new selective neuromuscular blockade (NMB) binding agent that anesthesiologists can use to achieve immediate reversal of ...
Maiko Satomoto   +3 more
doaj   +1 more source

Exposure to Sevoflurane Affects the Development of Parvalbumin Interneurons in the Main Olfactory Bulb in Mice [PDF]

open access: yes, 2016
Sevoflurane is widely used in adult and pediatric patients during clinical surgeries. Although studies have shown that exposure to sevoflurane impairs solfactory memory after an operation, the neuropathological changes underlying this effect are not ...
Guohong Cai   +7 more
core   +1 more source

Evaluating the impact of a standardised pre‐operative patient management protocol on major post‐operative complications in dogs undergoing BOAS surgery

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives Obstructive sleep apnoea syndrome is a common human upper respiratory tract disease that resembles Brachycephalic Obstructive Airway Syndrome in dogs, and pre‐operative lifestyle changes are often recommended to minimise perioperative risk.
C. D. L. Webb   +3 more
wiley   +1 more source

Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]

open access: yes, 2009
Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G.   +2 more
core   +2 more sources

The Impact of Vatinoxan on the Concentrations of Medetomidine, Midazolam, and Fentanyl in Central Nervous System After Subcutaneous Co‐Administration in Rats

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Our aim was to investigate whether vatinoxan, a peripherally acting alpha2‐adrenoceptor antagonist, would affect the concentrations of medetomidine, midazolam, and fentanyl in the central nervous system after subcutaneous co‐administration. Twelve healthy male Wistar rats, aged between 13 and 15 weeks, were used in this study.
Juhana Honkavaara   +5 more
wiley   +1 more source

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