Results 111 to 120 of about 60,245 (274)

Evaluating the Impact of Clonidine and Midazolam Premedication on Emergence Delirium in Pediatric Patients

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Preoperative anxiety is common in children and is associated with emergence delirium—a distressing postoperative complication characterized by agitation and disorientation. Midazolam has long been the drug of choice for preoperative anxiolysis.
Anne Louise de Barros Garioud, Anwen Taplin, Yufei Shang, R. Nazim Khan, David Sommerfield, Neil Hauser, Aine Sommerfield, Britta S. von Ungern‐Sternberg   +7 more
wiley   +1 more source

General anesthesia with sevoflurane decreases myocardial blood volume and hyperemic blood flow in healthy humans [PDF]

, 2013
BACKGROUND Preservation of myocardial perfusion during general anesthesia is likely important in patients at risk for perioperative cardiac complications.
Boer, Christa, Bulte, Carolien S. E., Bouwman, R. Arthur, Heymans, Martijn W., Loer, Stephan A., de Marchi, Stefano F., Kamp, Otto, Vogel, Rolf, Slikkerveer, Jeroen   +8 more
core   +1 more source

Sugammadex-Enhanced Neuronal Apoptosis following Neonatal Sevoflurane Exposure in Mice

Anesthesiology Research and Practice, 2016
In rodents, neonatal sevoflurane exposure induces neonatal apoptosis in the brain and results in learning deficits. Sugammadex is a new selective neuromuscular blockade (NMB) binding agent that anesthesiologists can use to achieve immediate reversal of ...
Maiko Satomoto, Zhongliang Sun, Yushi U. Adachi, Koshi Makita   +3 more
doaj   +1 more source

Preoperative caudal blocks associated with decreased cumulative opioid requirements compared to postoperative caudal blocks in pediatric urologic surgery

UroPrecision, EarlyView.
Abstract Background Caudal blocks (CB) are a cornerstone of pediatric urologic surgery, providing effective analgesia while mitigating potential neurotoxicity associated with general anesthesia and opioids. However, the optimal timing of CB—preoperative versus postoperative—remains controversial.
Jordan L. Mendelson, William Brenseke, Diego Alvarez Vega, William Nguyen, Mohammed Shium, Saige Gitlin, Ronnie G. Fine, Steven C. Friedman, Mark Horowitz, Walter I. Weiss, Raghu Idupuganti, Jordan S. Gitlin   +11 more
wiley   +1 more source

Immunofluorescent image analysis in the hippocampus from mice with (Sevoflurane) or without (Control) sevoflurane inhalation. [PDF]

, 2016
(Left) The representative images in Sevoflurane and Control groups are shown. Note augmented the green fluorescence in the stratum radiatum and stratum oriens of the hippocampus CA1 region indicating the F-actin constitution in the Sevoflurane group. The
Guo-Gang Feng (511751), Maiko Satomoto (3121926), Motohiko Sato (219521), Emi Nakamura (3121929), Hisaki Hayashi (48679), Hiroyuki Kinoshita (3121932), Yoshihiro Fujiwara (80708)   +6 more
core   +1 more source

Sevoflurane pretreatment attenuates hypoxia/reoxygenation-induced cardiomyocyte apoptosis through activation of AKT/pim-1 and AKT/GSK3β signaling pathways

Biotechnology & Biotechnological Equipment, 2019
Myocardial ischemia-reperfusion injury (IRI) is a severe trauma which is characterized by inflammatory reaction, oxidative stress and cardiomyocyte apoptosis.
Wensheng Zhao, Tieshan Zhang, Lulu Xu, Yue Yang, Yingchao Wang, Zhenni Jiang   +5 more
doaj   +1 more source

Capture of isoflurane from anaesthetised dogs and cats following methadone, medetomidine and ketamine administration

Veterinary Record, EarlyView.
Abstract Background Volatile anaesthetic agents contribute to climate change, and reducing this impact is a commendable ambition. We evaluated the efficiency of a veterinary capture device for isoflurane (VET‐can/VET‐dock, SageTech Veterinary) in anaesthetised cats and dogs.
Florence Hillen, David Yates, Kate White
wiley   +1 more source

Biomonitoring occupational sevoflurane exposure at low levels by urinary sevoflurane and hexafluoroisopropanol. [PDF]

, 2014
This study aimed to correlate environmental sevoflurane levels with urinary concentrations of sevoflurane (Sev-U) or its metabolite hexafluoroisopropanol (HFIP) in order to discuss the main issues relating to which biomarker of sevoflurane exposure is ...
CARRIERI, MARIELLA, MACCA', ISABELLA, SCAPELLATO, MARIA LUISA, SALAMON, FABIOLA, BARTOLUCCI, GIOVANNI BATTISTA, Manno, M., MANNO, MAURIZIO, Maccà, Isabella, TREVISAN, ANDREA   +8 more
core   +1 more source

Gut Microbiota–Metabolite–Brain Axis Reconstitution Reverses Sevoflurane-Induced Social and Synaptic Deficits in Neonatal Mice

Research
Background: The mechanisms underlying social dysfunction caused by repeated sevoflurane in early life remain unclear. Whether the gut microbiota–metabolite–brain axis is involved in the mechanism of sevoflurane developmental neurotoxicity still lacks ...
Youyi Zhao, Sanxing Ma, Lirong Liang, Shuhui Cao, Ze Fan, Danyi He, Xiaotong Shi, Yao Zhang, Bing Liu, Meiting Zhai, Shengxi Wu, Fang Kuang, Hui Zhang   +12 more
doaj   +1 more source

Drug‐Induced Sleep Endoscopy in Children Predicts OSA Severity

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background While adenotonsillectomy (AT) is first line for pediatric obstructive sleep apnea (OSA), treatment failure is common. Drug‐induced sleep endoscopy (DISE) provides dynamic airway assessment, but its role in predicting OSA severity requires clarification. This study correlates DISE findings with polysomnographic severity. Objective To
Neemias Santos Carneiro, Antônio Carlos Marão, Renato Battistel Santana, Camila de Castro Corrêa, Silke Anna Theresa Weber   +4 more
wiley   +1 more source